产品分类/PRODUCT CLASSIFICATION
| 产品编号 | V6702 |
| 英文名称 | TSH |
| 中文名称 | 人促甲状腺激素α亚基单克隆抗体 |
| 克?隆?号 | 38B1 |
| 理论分子量 | 12.2kDa |
| 检测分子量 | 48 kDa |
| 细胞定位 | 分泌型蛋白? |
| 性????状 | Lyophilized or Liquid |
| 浓????度 | 1mg/ml |
| 缓?冲?液 | 0.01M PBS(pH7.4) |
| 保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 | The four human glycoprotein hormones chorionic gonadotropin (CG), luteinizing hormone (LH), follicle stimulating hormone (FSH), and thyroid stimulating hormone (TSH) are dimers consisting of alpha and beta subunits that are associated noncovalently. The alpha subunits of these hormones are identical, however, their beta chains are unique and confer biological specificity. The protein encoded by this gene is the alpha subunit and belongs to the glycoprotein hormones alpha chain family. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011] Function: Stimulates the ovaries to synthesize the steroids that are essential for the maintenance of pregnancy. Subunit: Heterodimer of a common alpha chain and a unique beta chain which confers biological specificity to thyrotropin, lutropin, follitropin and gonadotropin. Subcellular Location: Secreted. Similarity: Belongs to the glycoprotein hormones subunit alpha family. SWISS: P01215 Gene ID: 1081 Database links: Entrez Gene: 1081 Human SwissProt: P01215 Human 活性异二聚体糖蛋白激素促甲状腺素/促甲状腺激素/TSH、促黄体激素/促黄体生成素/LH、促卵泡素/促卵泡激素/FSH和绒毛膜促性腺激素/CG的共享α链。这些激素结合靶细胞上的特定受体，进而激活下游信号通路。 |
