产品编号 | V3305 |
英文名称 | NT-proBNP |
中文名称 | 脑纳素前体蛋白单克隆抗体 |
别????名 | Gamma brain natriuretic peptide; Natriuretic peptide brain type; Natriuretic peptide precursor B; Natriuretic peptides B; NPPB; NPPB protein; ANFB_HUMAN; Natriuretic peptides B.proBNP. ?? |
克?隆?号 | 6E1 |
理论分子量 | 8.5kDa |
细胞定位 | 分泌型蛋白? |
性????状 | Liquid |
浓????度 | >1mg/ml |
缓?冲?液 | 0.01M PBS(pH7.4) |
保存条件 | Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 | Brain natriuretic peptide (BNP), also known as B-type natriuretic peptide, is a hormone secreted by cardiomyocytes in the heart ventricles in response to stretching caused by increased ventricular blood volume. The 32-amino acid polypeptide BNP is secreted attached to a 76–amino acid N-terminal fragment in the prohormone called NT-proBNP (BNPT), which is biologically inactive. Once released, BNP binds to and activates the atrial natriuretic factor receptor NPRA, and to a lesser extent NPRB, in a fashion similar to atrial natriuretic peptide (ANP) but with 10-fold lower affinity. The biological half-life of BNP, however, is twice as long as that of ANP, and that of NT-proBNP is even longer, making these peptides better targets than ANP for diagnostic blood testing. SWISS: P16860 Gene ID: 4879 应用推荐(Capture-Detection):?V3305-V3306 |