产品分类/PRODUCT CLASSIFICATION
| 产品编号 | V5222 |
| 英文名称 | phospho-Tau (Thr231) |
| 中文名称 | 磷酸化微管相关蛋白单克隆抗体 |
| 别????名 | Tau (phospho T231); p-Tau (phospho T231); Tau(Phospho-Thr231); MAPT(phospho T231); p-Tau(Thr231); MAPT; Microtuble-associted protein Tau; AI413597; AW045860; DDPAC; Disinhibition dementia parkinsonism amyotrophy complex; FLJ31424; FTDP 17; FTDP17; G Protein beta 1 gamma 2 subunit interacting factor 1; G protein beta1/gamma2 subunit interacting factor 1; MAPTL; MGC134287; MGC138549; MGC156663; Microtubule associated protein tau isoform 4; MSTD; Mtapt; MTBT1; MTBT2; Neurofibrillary tangle protein; Paired helical filament tau; PHF tau; PHF-tau; PPND; pTau; RNPTAU; Tauopathy and respiratory failure, included; TAU_HUMAN.?? |
| 产品类型 | 磷酸化抗体? |
| 克?隆?号 | 4C10 |
| 理论分子量 | 46/79kDa |
| 细胞定位 | 细胞浆?细胞膜? |
| 性????状 | Liquid |
| 浓????度 | 1mg/ml |
| 缓?冲?液 | 0.01M PBS(pH7.4) |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 | Tau proteins are important Promotes microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Tau proteins subcellular located in the axons of neurons, in the cytoso l and in association with plasma membrane components. It expressed in neurons. PNS-tau is expressed in the peripheral nervous system while the others are expressed in the central nervous system. SWISS: P10636 Gene ID: 4137 Database links: Entrez Gene: 4137?Human Entrez Gene: 17762?Mouse Omim: 157140?Human SwissProt: P10636?Human SwissProt: P10637?Mouse Unigene: 101174?Human Unigene: 1287?Mouse Unigene: 2455?Rat?? |
