规格 | 价格 | 库存 |
---|---|---|
100ug | ¥ 2980.00 | 10 |
500ug | ¥ 9500.00 | 10 |
产品编号 | bs-42305P |
英文名称 | Recombinant human LC3B protein, N-His |
中文名称 | 重组人自噬微管相关蛋白轻链3 |
别????名 | LC3II; LC-3Ⅱ; ATG8F; Autophagy related protein LC3 B; Autophagy related ubiquitin like modifier LC3 B; Autophagy-related protein LC3 B; Autophagy-related ubiquitin-like modifier LC3 B; LC3B; MAP1 light chain 3 like protein 2; MAP1 light chain 3-like protein 2; MAP1A/1B light chain 3 B; MAP1A/1BLC3; MAP1A/MAP1B LC3 B; MAP1A/MAP1B light chain 3 B; MAP1ALC3; MAP1LC3B a; MAP1LC3B; Microtubule associated protein 1 light chain 3 beta; Microtubule associated proteins 1A/1B light chain 3B; Microtubule-associated protein 1 light chain 3 beta; Microtubule-associated proteins 1A/1B light chain 3B; MLP3B_HUMAN?? |
理论分子量 | 13kDa |
性????状 | Lyophilized or Liquid |
浓????度 | >1mg/ml |
物????种 | Human |
序????列 | 1-125/125 |
纯????度 | >90% as determined by SDS-PAGE |
内毒素 | Not analyzed |
表达系统 | E.coli |
标签 | N-His |
缓?冲?液 | 20mM Tris-Hcl (pH=8.0) with 150mM Nacl |
保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 | A major contributor to cellular homeostasis is the ability of the cell to strike a balance between the formation and degradation/removal of its cellular components. This process of internal cellular turn-over is called autophagy (self-eating), and is facilitated by a pathway of around 16 interacting proteins in the human. LC3, a ubiquitin-like modifier protein, is the human homolog of yeast Apg8 and is involved in the formation of autophagosomal vacuoles, called autophagosomes. LC3 is expressed as 3 splice variants (LC3A, LC3B and LC3C), which exhibit different tissue distributions and are processed into cytosolic and autophagosomal membrane-bound forms, termed LC3-I and LC3-II, respectively. A disruption to the autophagic process is now associated with the progression of several cancers, neurodegenerative disorders and cardiac pathologies, where LC3 is widely employed as a marker for autophagy. SWISS: Q9GZQ8 Gene ID: 81631 |
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