产品分类/PRODUCT CLASSIFICATION
| 规格 | 价格 | 库存 |
|---|---|---|
| 100ug | ￥ 4800.00 | 10 |
| 500ug | ￥ 15000.00 | 10 |
| 产品编号 | bs-43200P |
| 英文名称 | Recombinant human C1Q protein, C-His (HEK293) |
| 中文名称 | 重组人补体C1Q蛋白 |
| 别????名 | Complement C1q subcomponent subunit A; Complement C1q subcomponent subunit B; Complement C1q subcomponent subunit C; C1QA_HUMAN; C1QB_HUMAN; C1QC_HUMAN;?? |
| 理论分子量 | 48.4kDa |
| 性????状 | Lyophilized or Liquid |
| 浓????度 | >0.5mg/ml |
| 物????种 | Human |
| 纯????度 | >90% as determined by SDS-PAGE |
| 纯化方法 | AC |
| 内毒素 | Not analyzed |
| 表达系统 | HEK293 cell |
| 标签 | C-His |
| 缓?冲?液 | PBS (pH=7.4) |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 | C1q, a subcomponent of the classical complement pathway, is composed of nine subunits that mediate classical complement activation and thereby play an important role in the immune response. Six of these subunits are disulfide-linked dimers of chains A and B, while three of these subunits, designated C1q-A through C1q-C, are disulfide-linked dimers of chain C. The presence of receptors for C1q on effector cells modulates its activity, which may be antibody-dependent or independent. Macrophages are the primary source of C1q, while anti-inflammatory drugs as well as cytokines differentially regulate expression of the mRNA as well as the protein. However, its ability to modulate the interaction of platelets with collagen and immune complexes suggests C1q influences homeostasis as well as other immune activities, and perhaps thrombotic complications resulting from immune injury. Defects in C1q-A, C1q-B and C1q-C cause inactivation of the classical pathway, leading to a rare genetic disorder characterized by lupus-like symptoms. SWISS: P02747 Gene ID: 712 |
| 产品图片 |  The purity of the protein is greater than 90% as determined by reducing SDS-PAGE. |
