产品分类/PRODUCT CLASSIFICATION
| 产品编号 | bs-43202P |
| 英文名称 | Recombinant human SHBG protein (HEK293), His |
| 中文名称 | 重组人性激素结合球蛋白 |
| 别????名 | Sex Hormone Binding Globulin; ABP; Androgen binding protein; SBP; Sex steroid binding protein; SHBG; TEBG; Testis specific androgen binding protein; Testosterone binding beta globulin; Testosterone Estradiol Binding Globulin; Testosterone estrogen binding globulin; SHBG_HUMAN; Sex hormone-binding globulin; Sex steroid-binding protein; Testis-specific androgen-binding protein; Testosterone-estradiol-binding globulin; TeBG; Testosterone-estrogen-binding globulin.?? |
| 理论分子量 | 41.5kDa |
| 性????状 | Lyophilized or Liquid |
| 浓????度 | >0.5mg/ml |
| 物????种 | Human |
| 序????列 | 30-402/402 |
| 纯????度 | >90% as determined by SDS-PAGE |
| 纯化方法 | AC |
| 内毒素 | Not analyzed |
| 表达系统 | HEK293 cell |
| 标签 | C-His |
| 缓?冲?液 | PBS (pH=7.4) |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 | Sex hormone binding globulin (SHBG) is a glycoprotein synthesized by the liver. Circulating androgen and estrogen concentrations influence SHBG synthesis. Elevated testosterone, for example, causes SHBG synthesis to decrease, whereas high estrogen stimulates SHBG production. The regulation of SHBG synthesis, combined with SHBG's higher affinity for testosterone, impacts bioavailable testosterone levels. SHBG binds up to 98 percent of the steroid hormones in the blood including 5a-dihydrotestosterone (DHT), testosterone and androstenediol with particularly high affinity, and estradiol and estrone with slightly lower affinity. SWISS: A0A6P7EHR7 Gene ID: 101102995 性激素结合球蛋白(SHBG),又称睾酮—雌二醇结合球蛋白。 SHBG是一运输性激素的载体，它在性激素人作用过程中以及在各种生理病理情况下都有一定的变化和意义。 SHBG是由母体肝脏产生的循环类固醇类结合球蛋白，执行载体蛋白的功能，胰岛素是肝脏合成SHBG的强大的抑制因子，胰岛素抑制效应的主要作用点在于竞争性刺激肝脏SHBG的产生，因而SHBG减少是高胰岛素血症、胰岛素抵抗的标志。 |
| 产品图片 |  The purity of the protein is greater than 90% as determined by reducing SDS-PAGE. |
