产品分类/PRODUCT CLASSIFICATION
| 产品编号 | bs-42277P |
| 英文名称 | Recombinant human COL10A1 protein, N-His |
| 中文名称 | 重组人Ⅹ型胶原蛋白 |
| 别????名 | Collagen type X; Col10a 1; Collagen alpha 1(X) chain; Collagen type X alpha 1 (Schmid metaphyseal chondrodysplasia); Collagen type X alpha 1; Collagen X alpha 1 polypeptide; CollagenX; fa66d11; fb10c08; OTTHUMP00000040411; Procollagen type X alpha 1; Schmid metaphyseal chondrodysplasia; wu:fa66d11; wu:fb10c08; COAA1_HUMAN; COL10A1; Collagen alpha-1(X) chain; collagen alpha-1(X) chain precursor; Schmid metaphyseal chondrodysplasia; collagen X, alpha-1 polypeptide.?? |
| 理论分子量 | 19.8kDa |
| 性????状 | Lyophilized or Liquid |
| 浓????度 | >1mg/ml |
| 物????种 | Human |
| 序????列 | 521-680/680 |
| 纯????度 | >90% as determined by SDS-PAGE |
| 纯化方法 | AC |
| 内毒素 | Not analyzed |
| 表达系统 | E.coli |
| 标签 | N-His |
| 缓?冲?液 | 20mM Tris-Hcl (pH=8.0) |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 | This gene encodes the alpha chain of type X collagen, a short chain collagen expressed by hypertrophic chondrocytes during endochondral ossification. Unlike type VIII collagen, the other short chain collagen, type X collagen is a homotrimer. Mutations in this gene are associated with Schmid type metaphyseal chondrodysplasia (SMCD) and Japanese type spondylometaphyseal dysplasia (SMD). [provided by RefSeq, Jul 2008]. SWISS: A1L4P2 Gene ID: 1300 Ⅹ型胶原是一种短链的非纤维性胶原，正常存在于软骨化骨中心及骨骺软骨生长板内，仅见于软骨细胞肥大区及钙化区前沿，在关节软骨见于钙化软骨层，由肥大软骨细胞特异表达，只短暂出现，可能参与软骨钙化的调节，是正常和异常骨形成的标志。 有学者认为：Ⅹ型胶原在骨性关节病中可作为软骨细胞表型不可逆转的诊断标志 ，是大量关节软骨细胞发生凋亡，最终导致关节软骨变薄，关节下骨变硬、增厚的主要原因。 |
| 产品图片 |  The purity of the protein is greater than 90% as determined by reducing SDS-PAGE. |
