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重组人信号转导和转录激活因子3蛋白
产品名称:
重组人信号转导和转录激活因子3蛋白
英文名称:
Recombinant human STAT3 protein, N-His
产品类别:
蛋白多肽
产品编号:
bs-42288P
保存条件:
20mM Tris-Hcl (pH=8.0) with 8M Urea
[价格]
规格 价格 库存
100ug ¥ 2980.00 10
500ug ¥ 9500.00 10

产品详情

产品编号bs-42288P
英文名称Recombinant human STAT3 protein, N-His
中文名称重组人信号转导和转录激活因子3蛋白
别????名1110034C02Rik; Acute Phase Response Factor; APRF; AW109958; DNA binding protein APRF; FLJ20882; HIES; MGC128731; MGC16063; MGC93551; Signal transducer and activator of transcription 3 (acute-phase response factor); Signal transducer and activator of transcription 3; Signal Transductor and Activator of Transcription 3; STAT 3; Transcription factor; STAT3_HUMAN.??
理论分子量29.3kDa
性????状Liquid
浓????度>1mg/ml
物????种Human
序????列2-219/770
纯????度>90% as determined by SDS-PAGE
纯化方法AC
内毒素Not analyzed
表达系统E.coli
标签N-His
保存条件20mM Tris-Hcl (pH=8.0) with 8M Urea
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of this protein. PIAS3 protein is a specific inhibitor of this protein. Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Sep 2015]

SWISS:
P40763

Gene ID:
7083

转录调节因子(Transcriptin Regulators)
产品图片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.

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