产品编号 | bs-42187P |
英文名称 | Recombinant human FIBIN protein, N-Trx-His |
中文名称 | 重组人FIBIN蛋白 |
别????名 | Fibin; FIBIN_HUMAN; Fin bud initiation factor homolog (zebrafish); Fin bud initiation factor homolog; MGC24932; PSEC0235.?? |
理论分子量 | 40.1kDa |
性????状 | Lyophilized or Liquid |
浓????度 | >1mg/ml |
物????种 | Human |
序????列 | 19-211/211 |
纯????度 | >90% as determined by SDS-PAGE |
纯化方法 | AC |
表达系统 | E.coli |
活性 | Not analyzed |
标签 | N-Trx-His |
缓?冲?液 | 20mM Tris-Hcl (pH=8.0) |
保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 | FIBIN (Fin bud initiation factor homolog) is a 211 amino acid protein involved in fin initiation in zebrafish. The human homolog is encoded by a gene that maps to chromosome 11, which makes up around 4% of human genomic DNA and is considered a gene and disease association dense chromosome. The chromosome 11 encoded Atm gene is important for regulation of cell cycle arrest and apoptosis following double strand DNA breaks. Atm mutation leads to the disorder known as ataxia-telangiectasia. The blood disorders Sickle cell anemia and β thalassemia are caused by HBB gene mutations. Wilms' tumors, WAGR syndrome and Denys-Drash syndrome are associated with mutations of the WT1 gene. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are also associated with defects in chromosome 11.
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产品图片 | The purity of the protein is greater than 90% as determined by reducing SDS-PAGE. |
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