产品分类/PRODUCT CLASSIFICATION
| 规格 | 价格 | 库存 |
|---|---|---|
| 100ug | ￥ 4800.00 | 10 |
| 500ug | ￥ 15000.00 | 10 |
| 产品编号 | bs-43588P |
| 英文名称 | Recombinant human EPOR protein, C-His (HEK293) |
| 中文名称 | 重组人红细胞生成素受体蛋白 |
| 别????名 | erythropoietin receptor; EPO R; EPO Receptor; Erythropoietin receptor precursor; EPOR_HUMAN; MGC138358.?? |
| 理论分子量 | 25.9kDa |
| 性????状 | Lyophilized or Liquid |
| 浓????度 | >0.5mg/ml |
| 物????种 | Human |
| 纯????度 | >90% as determined by SDS-PAGE |
| 纯化方法 | AC |
| 内毒素 | Not tested |
| 表达系统 | HEK293 cell |
| 标签 | C-His |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 | The erythropoietin receptor (EPOR) is a member of the cytokine receptor family. There are several isoforms including: EPOR-F (full length), EPOR-S (soluble form), and EPOR-T (truncated form). Upon erythropoietin (EPO) binding, the EPOR activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated EPOR appears to have a role in erythroid cell survival. Defects in the EPOR may produce erythroleukemia and familial erythrocytosis. A functional EPOR is found in the cardiovascular system, including endothelial cells and cardiomyocytes, and data suggest that the EPO/EPO receptor system plays an important role in cardiac function. In animal studies, treatment with EPO during ischemia/reperfusion in the heart has been shown to limit the infarct size and the extent of apoptosis. SWISS: P19235 Gene ID: 2057 |
| 产品图片 |  The purity of the protein is greater than 90% as determined by reducing SDS-PAGE. |
