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重组人低分子量神经丝蛋白
产品名称:
重组人低分子量神经丝蛋白
英文名称:
Recombinant human NF-L protein, N-His
产品类别:
蛋白多肽
产品编号:
bs-44004P
保存条件:
Shipped at 4℃. Store at -20 °C for one year. Avoid
[价格]
规格 价格 库存
100ug ¥ 2980.00 10
500ug ¥ 9500.00 10

产品详情

产品编号bs-44004P
英文名称Recombinant human NF-L protein, N-His
中文名称重组人低分子量神经丝蛋白
别????名Neurofilament L; Neurofilament 68; Neurofilament triplet L; 70 kD Neurofilament Light; 68kDa neurofilament protein; CMT 1F; CMT 2E; CMT1F; CMT2E; FLJ53642; Light molecular weight neurofilament protein; NEFL; Neurofilament light; Neurofilament light polypeptide 68kDa; Neurofilament light polypeptide; Neurofilament protein, light chain; Neurofilament subunit NF L; Neurofilament triplet L protein; NF 68; NF L; NF68; NFL; NFL_HUMAN??
理论分子量52.6kDa
性????状Lyophilized or Liquid
浓????度>0.5mg/ml
物????种Human
纯????度>90% as determined by SDS-PAGE
表达系统E.coli
标签N-His
缓?冲?液20 mM Tris-HCl (pH=8.0)
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍Neurofilament light polypeptide also called NF-L; Neurofilament triplet L protein; 68 kDa neurofilament protein. Neurofilaments usually contain three intermediate filament proteins: L, M, and H which are involved in the maintenance of neuronal caliber. The extra mass and high charge density that distinguish the neurofilament proteins from all other intermediate filament proteins are due to the tailpiece extensions. This region may form a charged scaffolding structure suitable for interaction with other neuronal components or ions. NF-L is the most abundant of the three neurofilament proteins and, as the other nonepithelial intermediate filament proteins, it can form homopolymeric 10-nm filaments. Belongs to the intermediate filament family.

SWISS:
P07196

Gene ID:
4747

神经生物学相关蛋白(Neurobiology)
低分子量神经丝蛋白,简称NF-L,分子量为68kDa,NF-L的聚集与神经退行性疾病的发病机理相关,如运动神经元的降解等。
神经纤丝蛋白的功能是提供弹性使神经纤维易于伸展和防止断裂。
神经丝是中间纤维的一种重要类型又称神经微丝蛋白,特异地在神经细胞内表达,并在轴突内相互平行排列成束. 哺乳动物的神经丝由3种蛋白组成:
低分子量神经丝蛋白,简称NF-L;分子量为68kDa;
中分子量神经丝蛋白,简称NF-M;分子量为160kDa;
高分子量神经丝蛋白,简称NF-H,分子量为200 kDa。
产品图片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.

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