规格 | 价格 | 库存 |
---|---|---|
10ug | ¥ 2080.00 | 10 |
50ug | ¥ 6800.00 | 10 |
500ug | ¥ 28000.00 | 10 |
产品编号 | bs-48033P |
英文名称 | Recombinant human IL-21 protein (Active, HEK293) |
中文名称 | 重组人白介素-21(活性的) |
别????名 | Human IL-21;IL-21;h-IL-21;rh-IL-21;recombinant human IL-21;recombinant IL-21;IL;interluekin;Recombinant human IL-21 protein (Active, HEK293)?? |
检测分子量 | 15 kDa |
性????状 | Lyophilized powder |
浓????度 | >0.5 mg/ml |
物????种 | Human |
序????列 | 1-132/162 |
纯????度 | >95% as determined by SDS-PAGE |
纯化方法 | AC |
内毒素 | <0.5 EU/μg as determined by LAL. |
表达系统 | HEK293 cell |
活性 | Yes |
标签 | Tag free |
保存条件 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after reconstitution. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 | IL-21 is a typical family I cytokine with broad pleiotropic actions and is primarily produced by T follicular helper cells, Th17, and natural killer T cells in response to antigenic stimulation. Il-21 generally enhances antigen-specific responses of immune cells. It controls the activation, proliferation, differentiation, cytotoxicity, and survival of various target immune cells. Additionally, IL-21 promotes the anti-tumor activity of CD8+ T-cells and NK cells. IL-21 elicits its effect through binding to IL-21R, which also contains the gamma chain found in other cytokine receptors such as IL-2, IL-4, IL-7, IL-9 and IL-15. IL-21/IL-21R interaction triggers a cascade of events, which includes activation of the tyrosine kinases JAK1 and JAK3, followed by activation of the transcription factors STAT1 and STAT3. Recombinant Human IL-21 is a 15.4 kDa protein consisting of 132 amino acid residues. SWISS: Q9HBE4 Gene ID: 59067 |