| 产品编号 | Y-0492 |
| 英文名称 | SAAP-148 peptide |
| 中文名称 | SAAP-148抗菌肽 |
| 别????名 | P148; SAAP 148?? |
| 理论分子量 | 3.268kDa |
| 性????状 | Lyophilized powder |
| 序????列 | LKRVWKRVFKLLKRYWRQLKKPVR-NH2 |
| 纯化方法 | HPLC |
| 活性 | Yes |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 | SAAP 148 is a synthetic peptide derived from LL-37 which is more stable to plasma proteases and more effective in eradicating bacteria than the parent peptide. In vitro, SAAP (synthetic antimicrobial and antibiofilm peptide) 148 kills MDR pathogens without inducing resistance, prevents biofilm formation, and eliminates established biofilms and persister cells. A single 4-hour treatment with SAAP 148 completely eradicates acute and established biofilm associated infections with methicillin resistant Staphylococcus aureus and MDR Acinetobacter baumannii from wounded ex vivo human skin and murine skin in vivo
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