规格 | 价格 | 库存 |
---|---|---|
100ug | ¥ 880.00 | 10 |
500ug | ¥ 2980.00 | 10 |
产品编号 | bs-21741P |
英文名称 | Copeptin Active Peptide |
中文名称 | 抗利尿激素/血管升压素/加压素/血管加压素封闭多肽 |
别????名 | Vasopressin; Antidiuretic Hormone; Arginine Vasopressin; ADH; Arginine vasopressin neurophysin II; ARVP; AVP; AVP NPII; AVRP; Vasopressin neurophysin 2 copeptin precursor; Vasopressin neurophysin II copeptin; VP.?? |
性????状 | Lyophilized powder |
物????种 | human |
序????列 | SDRSNATQLDGPAGALLLRLVQLAGAPEPFEPAQPDAY |
纯化方法 | HPLC |
活性 | Not tested |
保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 | Vasopressin, also known as arginine vasopressin (AVP) or antidiuretic hormone (ADH), is a posterior pituitary hormone that is synthesised in the hypothalamus. Vasopressin is synthesised as a precursor protein that consists of arginine vasopressin and two associated proteins, neurophysin 2 and the glycopeptide copeptin. Vasopressin, together with its carrier protein neurophysin II, is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. Vasopressin acts as a growth factor by enhancing pH regulation through acid-base transport systems. It has a direct antidiuretic action on the kidney and also causes vasoconstriction of the peripheral vessels. Vasopressin can also contract smooth muscle during parturition and lactation. It also plays a role in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions. Mutations in the vasopressin precursor cause autosomal dominant neurohypophyseal diabetes insipidus (ADNDI), which is characterised by persistant thirst, polydipsia and polyuria. SWISS: P01185 Gene ID: 551 |