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醋酸阿拉瑞林
产品名称:
醋酸阿拉瑞林
英文名称:
Alarelin, Acetate
产品类别:
蛋白多肽
产品编号:
bs-37001P
保存条件:
Shipped at 4℃. Stored at -20℃ for one year. Avoid
[价格]
规格 价格 库存
1mg ¥ 2380.00 10

产品详情

产品编号bs-37001P
英文名称Alarelin, Acetate
中文名称醋酸阿拉瑞林
别????名ALARELIN ACETATE; DES-GLY10,[D-ALA6]-LH-RH ETHYLAMIDE ACETATE SALT; 79561-22-1; 148029-26-9; MFCD18782231; (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH acetate??阿拉瑞林;丙氨瑞林;醋酸阿拉瑞林;腺苷-5-一磷酸;
性????状Lyophilized powder
序????列Pyr-HWSY(d-A)LRP-NHEt
纯化方法HPLC
活性Yes
保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍Alarelin (Gonadotrophin-releasing hormone) is a synthetic LH-RH agonist that is found in higher amounts than that of LH-RH in rat hypophyseal stimulation of gonadotropin secretion in vivo and in vitro and in ovulation inductions. Alarelin is known for its induction of ovulation. Alarelin acetate is the acetate form of a hypothalamic peptide that stimulates the release of FSH and LH from the pituitary gland.
Alarelin acetate peptide is a single, non-glycosylated polypeptide chain containing 9 amino acids, having a molecular mass of 1167.3 Dalton and a Molecular formula of C56H78N16O12 x C2H4O2. The CAS No. is 79561-22-1.


阿拉瑞林(gonadotrophin releasing hormoneanalogue(GnRH-A),又名丙氨瑞林,为人工合成的促性腺激素释放激素(GnRH)的九肽类似物,其药效是母体的15倍。用药初期可刺激垂体释放促黄体生成素(LH)和促卵泡素(FSH),引起卵巢源性甾体激素短暂升高;重复用药可抑制垂体释放LH和FSH,使血中的雌二醇水平下降,达到药物去卵巢的作用,同时对子宫内膜癌的相关癌基因 ras、neu、myc 的表达具有调控作用。临床上主要用于促排卵、治疗卵巢功能异常引起的不育症、子宫内膜异位症及子宫肌瘤等和提高妊娠率。

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