规格 | 价格 | 库存 |
---|---|---|
1mg | ¥ 2380.00 | 10 |
产品编号 | bs-37001P |
英文名称 | Alarelin, Acetate |
中文名称 | 醋酸阿拉瑞林 |
别????名 | ALARELIN ACETATE; DES-GLY10,[D-ALA6]-LH-RH ETHYLAMIDE ACETATE SALT; 79561-22-1; 148029-26-9; MFCD18782231; (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH acetate??阿拉瑞林;丙氨瑞林;醋酸阿拉瑞林;腺苷-5-一磷酸; |
性????状 | Lyophilized powder |
序????列 | Pyr-HWSY(d-A)LRP-NHEt |
纯化方法 | HPLC |
活性 | Yes |
保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 | Alarelin (Gonadotrophin-releasing hormone) is a synthetic LH-RH agonist that is found in higher amounts than that of LH-RH in rat hypophyseal stimulation of gonadotropin secretion in vivo and in vitro and in ovulation inductions. Alarelin is known for its induction of ovulation. Alarelin acetate is the acetate form of a hypothalamic peptide that stimulates the release of FSH and LH from the pituitary gland. Alarelin acetate peptide is a single, non-glycosylated polypeptide chain containing 9 amino acids, having a molecular mass of 1167.3 Dalton and a Molecular formula of C56H78N16O12 x C2H4O2. The CAS No. is 79561-22-1. 阿拉瑞林(gonadotrophin releasing hormoneanalogue(GnRH-A),又名丙氨瑞林,为人工合成的促性腺激素释放激素(GnRH)的九肽类似物,其药效是母体的15倍。用药初期可刺激垂体释放促黄体生成素(LH)和促卵泡素(FSH),引起卵巢源性甾体激素短暂升高;重复用药可抑制垂体释放LH和FSH,使血中的雌二醇水平下降,达到药物去卵巢的作用,同时对子宫内膜癌的相关癌基因 ras、neu、myc 的表达具有调控作用。临床上主要用于促排卵、治疗卵巢功能异常引起的不育症、子宫内膜异位症及子宫肌瘤等和提高妊娠率。 |