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磷酸化蛋白激酶B封闭多肽
产品名称:
磷酸化蛋白激酶B封闭多肽
英文名称:
phospho-AKT1+AKT2 (Thr308+Thr309) Antibody Blocking Peptide
产品类别:
蛋白多肽
产品编号:
bs-5182P
保存条件:
Shipped at 4℃. Stored at -20℃ for one year. Avoid
[价格]
规格 价格 库存
500ug ¥ 1080.00 10

产品详情

产品编号bs-5182P
英文名称phospho-AKT1+AKT2 (Thr308+Thr309) Antibody Blocking Peptide
中文名称磷酸化蛋白激酶B封闭多肽
别????名AKT1 (phospho T308); AKT2 (phospho T309); AKT3 (phospho T305); p-AKT1 (phospho T308); p-AKT2 (phospho T309); p-AKT3 (phospho T305); AKT 1; AKT; AKT1; AKT-1; AKT1_HUMAN; AKT 2; AKT2; AKT-2; AKT2_HUMAN; AKT 3; AKT3; AKT-3; AKT3_HUMAN; C AKT; cAKT; MGC9965; MGC99656; Oncogene AKT1; PKB; PKB alpha; PKB-ALPHA; PKB beta; PKB gamma; PRKBA; Protein Kinase B Alpha; Protein kinase B; Proto-oncogene c-Akt; RAC Alpha; RAC alpha serine/threonine protein kinase; RAC; RAC PK Alpha; Rac protein kinase alpha; RAC Serine/Threonine Protein Kinase; RAC-alpha serine/threonine-protein kinase; RAC-PK-alpha; v akt murine thymoma viral oncogene homolog 1; vAKT Murine Thymoma Viral Oncogene Homolog 1.??
性????状Lyophilized powder
物????种human
纯化方法HPLC
活性Not tested
保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍AKT, also known as protein kinase B (PKB), is a 57 kDa serine/threonine protein kinase. There are three mammalian isoforms of Akt: AKT1 (PKB alpha), AKT2 (PKB beta) and AKT3 (PKB gamma) with AKT2 and AKT3 being approximately 82% identical with the AKT1 isoform. Each isoform has a pleckstrin homology (PH)domain, a kinase domain and a carboxy terminal regulatory domain. AKT was originally cloned from the retrovirus AKT8, and is a key regulator of many signal transduction pathways. Its tight control over cell proliferation and cell viability are manifold; overexpression or inappropriate activation of AKT has been seen in many types of cancer. AKT mediates many of the downstream events of phosphatidylinositol 3 kinase (a lipid kinase activated by growth factors, cytokines and insulin). PI3 kinase recruits AKT to the membrane, where it is activated by PDK1 phosphorylation. Once phosphorylated, AKT dissociates from the membrane and phosphorylates targets in the cytoplasm and the cell nucleus.

SWISS:
P31749

Gene ID:
207

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