上海细胞库
人源细胞系| 稳转细胞系| 基因敲除株| 基因点突变细胞株| 基因过表达细胞株| 重组细胞系| 猪的细胞系| 马细胞系| 兔的细胞系| 犬的细胞系| 山羊的细胞系| 鱼的细胞系| 猴的细胞系| 仓鼠的细胞系| 狗的细胞系| 牛的细胞| 大鼠细胞系| 小鼠细胞系| 其他细胞系|
人源细胞系| 稳转细胞系| 基因敲除株| 基因点突变细胞株| 基因过表达细胞株| 重组细胞系| 猪的细胞系| 马细胞系| 兔的细胞系| 犬的细胞系| 山羊的细胞系| 鱼的细胞系| 猴的细胞系| 仓鼠的细胞系| 狗的细胞系| 牛的细胞| 大鼠细胞系| 小鼠细胞系| 其他细胞系|
| 规格 | 价格 | 库存 |
|---|---|---|
| 500ug | ￥ 880.00 | 10 |
| 产品编号 | bs-1005P |
| 英文名称 | CK2 Antibody Blocking Peptide |
| 中文名称 | 细胞角蛋白2封闭多肽 |
| 别????名 | CK2; Cytokeratin 2; KRT2B; keratin 76; CK 2P; CK2P; Cytokeratin 2P; Cytokeratin2; Cytokeratin2P; HUMCYT 2A; HUMCYT2A; K2P; Keratin 2p; Keratin 76; Keratin type II cytoskeletal 2 ora; Keratin2p; Keratin76; KRT 2B;KRT 2P; KRT 76; KRT2B; KRT2P; KRT76; K22O_HUMAN.?? |
| 性????状 | Lyophilized powder |
| 物????种 | human |
| 纯化方法 | HPLC |
| 活性 | Not tested |
| 保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
| 产品介绍 | Keratins are a group of water-insoluble proteins that form monofilaments, a class of intermediate filament. These filaments form part of the cytoskeletal complex in epidermis and in most other epithelial tissues. Nineteen human epithelial keratins are resolved with two-dimensional gels electrophoresis (1). These can be divided into acid (pI <5.7) and basic (pI >6.0) subfamilies. The acidic keratins have molecular weights of 56.5, 55, 51, 50, 50’, 48, 46, 45 and 40 kD. The basic keratins have molecular weights of 65-67, 64, 59, 58, 56 and 52kD. Members of the acidic and basic subfamilies are found together in pairs. The composition of keratin pairs varies with the epithelial cell type, stage of differentiation, cellular growth environment, and disease state (2-4). The 56.5/65-67kD pair is present in keratinized (differentiated) epidermis. The 55/64kD pair is characteristic of normal (corneal-type) epithelial differentiation (1,2). The 51/59kD pair is characteristic of the stratified squamous epithelial of internal organism such as esophagus and tongue (1,3). The 51/58kD pair is a keratinocyte marker; this pair is present in almost all stratified epithelia irrespective of the state of cellular stratification (1,2). The 48/56kD pair is characteristic of hyperproliferative (de-differentiated) keratinocytes (1,5). The 45/52kD pair and to a lesser extent, the 46/54kD pair are characteristic of simple epithelia (1). The 40kD keratin is present in most epithelia except adult epidermis (1). SWISS: P35908 Gene ID: 51350 |
