规格 | 价格 | 库存 |
---|---|---|
500ug | ¥ 880.00 | 10 |
产品编号 | bs-0180P |
英文名称 | DDC Antibody Blocking Peptide |
中文名称 | 多巴胺脱羧酶封闭多肽 |
别????名 | AADC; DDC; Aromatic L Amino Acid Decarboxylase; DDC protein; DOPA decarboxylase; aromatic-L-amino-acid decarboxylase isoform 1; DDC_HUMAN.?? |
性????状 | Lyophilized powder |
物????种 | human |
纯化方法 | HPLC |
活性 | Not tested |
保存条件 | Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles. |
产品介绍 | bs-0180P is one synthetic peptide derived from human DDC. DOPA decarboxylase is an enzyme implicated in 2 metabolic pathways, synthesizing 2 important neurotransmitters: dopamine and serotonin which both play key roles in many clinical disorders, including Parkinson's disease. Following the hydroxylation of tyrosine to form L dihydroxyphenylalanine (LDOPA), catalyzed by tyrosine hydroxylase, DDC decarboxylates LDOPA to form dopamine. This neurotransmitter is found in different areas of the brain and is particularly abundant in basal ganglia. Dopamine is also produced by DDC in the sympathetic nervous system and is the precursor of the catecholaminergic hormones, noradrenaline and adrenaline in the adrenal medulla. In the nervous system, tryptophan hydroxylase produces 5 OH tryptophan, which is decarboxylated by DDC, giving rise to serotonin. DDC is a homodimeric, pyridoxal phosphate dependent enzyme. SWISS: P20711 Gene ID: 1644 |