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5-脂氧合酶封闭多肽
产品名称:
5-脂氧合酶封闭多肽
英文名称:
5-LOX Antibody Blocking Peptide
产品类别:
蛋白多肽
产品编号:
bs-0526P
保存条件:
Shipped at 4℃. Stored at -20℃ for one year. Avoid
[价格]
规格 价格 库存
500ug ¥ 880.00 10

产品详情

产品编号bs-0526P
英文名称5-LOX Antibody Blocking Peptide
中文名称5-脂氧合酶封闭多肽
别????名5-lipoxygenase; 5-LOX; 5 LO; 5LPG; ALOX 5; Arachidonate 5 lipoxygenase; Arachidonic acid 5 lipoxygenase; Leukotriene A4 synthase; LOG 5; LOG5; MGC163204; LOX5_HUMAN.??
性????状Lyophilized powder
物????种human
纯化方法HPLC
活性Not tested
保存条件Shipped at 4℃. Stored at -20℃ for one year. Avoid repeated freeze/thaw cycles.
产品介绍This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.

SWISS:
P48999

Gene ID:
240

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