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重组人细胞死亡激活剂CIDEB蛋白
产品名称:
重组人细胞死亡激活剂CIDEB蛋白
英文名称:
Recombinant human CIDEB protein, C-His
产品类别:
蛋白多肽
产品编号:
bs-42071P
保存条件:
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw
[价格]
规格 价格 库存
100ug ¥ 2980.00 10
500ug ¥ 9500.00 10

产品详情

产品编号bs-42071P
英文名称Recombinant human CIDEB protein, C-His
中文名称重组人细胞死亡激活剂CIDEB蛋白
别????名cell death activator CIDE-B; cell death-inducing DFFA-like effector B; Cide-b; CIDEB_HUMAN.??
性????状Lyophilized or Liquid
浓????度>1mg/ml
物????种Human
序????列39-179/219
纯????度>90% as determined by SDS-PAGE
纯化方法AC
内毒素Not tested
表达系统E.coli
标签C-His
缓?冲?液20mM Tris-Hcl (pH=8.0) with 8M Urea & 0.8M L-Arginine
保存条件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adapter molecules and members of the caspase family of proteases. These death signals finally cause the degradation of chromosomal DNA by activated DNase. DFF45/ICAD has been identified as an inhibitor of caspase activated DNase DFF40/CAD. DFF45 related proteins CIDE A and CIDE B were recently identified. CIDE contains a new type of domain termed CIDE N, which has high homology with the regulatory domains of DFF45/ICAD and DFF40/CAD. Expression of CIDE B induces apoptosis, which is inhibited by DFF45. CIDE B is a DFF45 inhibitable effector that promotes cell death and DNA fragmentation. CIDE B is expressed mainly in liver and small intestine and at lower levels in spleen, colon, kidney, peripheral blood lymphocytes, and bone marrow.

SWISS:
Q546V8

Gene ID:
27141

产品图片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.

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