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重组人组织相容性复合体蛋白
产品名称:
重组人组织相容性复合体蛋白
英文名称:
Recombinant human HLA-B & Beta-2-MG Heterodimer protein, His&Avi (HEK293)
产品类别:
蛋白多肽
产品编号:
bs-43160P
保存条件:
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw
[价格]
规格 价格 库存
100ug ¥ 4800.00 10
500ug ¥ 15000.00 10

产品详情

产品编号bs-43160P
英文名称Recombinant human HLA-B & Beta-2-MG Heterodimer protein, His&Avi (HEK293)
中文名称重组人组织相容性复合体蛋白
别????名HLAB_HUMAN; HLA class I histocompatibility antigen, B alpha chain; Human leukocyte antigen B (HLA-B); HLAB; ??
理论分子量35.8kDa
性????状Lyophilized or Liquid
浓????度>0.5mg/ml
物????种Human
纯????度>90% as determined by SDS-PAGE
内毒素Not analyzed
表达系统HEK293 cell
活性Not tested
标签C-His&Avi
缓?冲?液PBS (pH=7.4)
保存条件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon 1 encodes the leader peptide, exon 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region and exons 6 and 7 encode the cytoplasmic tail. Polymorphisms within exon 2 and exon 3 are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. Hundreds of HLA-B alleles have been described. [provided by RefSeq, Jul 2008]

SWISS:
P01889

Gene ID:
3106

产品图片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.

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