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重组小鼠一氧化氮合成酶-2蛋白
产品名称:
重组小鼠一氧化氮合成酶-2蛋白
英文名称:
Recombinant mouse Nos2 protein, N-His
产品类别:
蛋白多肽
产品编号:
bs-42164P
保存条件:
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw
[价格]
规格 价格 库存
100ug ¥ 2980.00 10
500ug ¥ 9500.00 10

产品详情

产品编号bs-42164P
英文名称Recombinant mouse Nos2 protein, N-His
中文名称重组小鼠一氧化氮合成酶-2蛋白
别????名i NOS; Nitric Oxide Synthase, Inducible; HEP NOS; Hepatocyte NOS; HEPNOS; Inducible nitric oxide synthase; Inducible NO synthase; Inducible NOS; INOS; Inosl; MAC NOS; Macrophage NOS; Nitric oxide synthase 2 inducible macrophage; Nitric oxide synthase 2A (inducible hepatocytes); Nitric oxide synthase inducible; NOS 2; NOS 2A; NOS; Nos II; NOS type II; Nos2; NOS2A; NOS2_Mouse.??
理论分子量42.8kDa
性????状Lyophilized or Liquid
浓????度>1mg/ml
物????种Mouse
纯????度>90% as determined by SDS-PAGE
纯化方法AC
内毒素Not analyzed
表达系统E.coli
活性Not tested
标签N-His
缓?冲?液20mM Tris(pH=8.0) with 8M Urea
保存条件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍Nitric oxide (NO) is an inorganic, gaseous free radical that carries a variety of messages between cells. Vasorelaxation, neurotransmission and cytotoxicity can all be potentiated through cellular response to NO. NO production is mediated by members of the nitric oxide synthase (NOS) family. NOS catalyzes the oxidization of L-arginine to produce L-citrulline and NO. Two constitutive isoforms, brain or neuronal NOS (b or nNOS, type I) & endothelial cell NOS (eNOS, type III), and one inducible isoform (iNOS, type II), have been cloned. All NOS isoforms contain calmodulin, nicotinamide adenine dinucleotide phosphate (NADPH), flavin adenine dinucleotide (FAD), and flavin mononucleotide (FMN) binding domains. Nitric oxide synthase is expressed in liver, macrophages, hepatocytes, synoviocytes, stimulated glial cells and smooth muscle cells. Cytokines such as interferon-gamma (IFN), tumor necrosis factor (TNF), interleukin-1 and -2, and lipopolysaccarides (LPS) cause an increase in iNOS mRNA, protein, and activity levels. Protein kinase C-stimulating agents exhibit the same effect on iNOS activity. After cytokine induction, iNOS exhibits a delayed activity response which is then followed by a significant increase in NO production over a long period of time. Human iNOS is regulated by calcium/calmodulin (in contrast with mouse NOS2).

SWISS:
P29477

Gene ID:
18126

产品图片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.

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