上海细胞库
人源细胞系| 稳转细胞系| 基因敲除株| 基因点突变细胞株| 基因过表达细胞株| 重组细胞系| 猪的细胞系| 马细胞系| 兔的细胞系| 犬的细胞系| 山羊的细胞系| 鱼的细胞系| 猴的细胞系| 仓鼠的细胞系| 狗的细胞系| 牛的细胞| 大鼠细胞系| 小鼠细胞系| 其他细胞系|
人源细胞系| 稳转细胞系| 基因敲除株| 基因点突变细胞株| 基因过表达细胞株| 重组细胞系| 猪的细胞系| 马细胞系| 兔的细胞系| 犬的细胞系| 山羊的细胞系| 鱼的细胞系| 猴的细胞系| 仓鼠的细胞系| 狗的细胞系| 牛的细胞| 大鼠细胞系| 小鼠细胞系| 其他细胞系|
| 规格 | 价格 | 库存 |
|---|---|---|
| 100ug | ￥ 2980.00 | 10 |
| 500ug | ￥ 9500.00 | 10 |
| 产品编号 | bs-42131P |
| 英文名称 | Recombinant human FMN1 protein, His |
| 中文名称 | 重组人肢体畸形相关蛋白FMN1 |
| 别????名 | FMN; Formin 1; Formin1; Formin-1; LD; Limb deformity protein homolog; FMN1_HUMAN.?? |
| 理论分子量 | 41.4kDa |
| 性????状 | Lyophilized or Liquid |
| 浓????度 | >1mg/ml |
| 物????种 | Human |
| 序????列 | 1-354/1419 |
| 纯????度 | >90% as determined by SDS-PAGE |
| 内毒素 | Not analyzed |
| 活性 | Not tested |
| 标签 | N-His |
| 缓?冲?液 | 20mM Tris (pH=8.0) with 2M Urea |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 | The temporal genetic hierarchy influencing normal limb development can deregulate and mediate mammalian developmental syndromes. In mice, the limb deformity (ld) locus influences normal limb development and gives rise to alternative mRNAs that can translate into a family of proteins known as formins. Formins play a crucial role in cytoskeletal reorganization by influencing Actin filament assembly. Formins co-localize with the actin cytoskeleton and can translocate into the cell cytosol and into the nucleus in an HGF-dependent manner. Vertebrate nuclear formins can control polarizing activity in limb buds through establishment of a Sonic hedgehog/FGF-4 feedback loop. Deficiency mutations at the mammalian ld locus lead to profound developmental defects in limb and kidney formation. The human Formin 1 and 2 genes map to chromosome 15q13.3 and 1q43, respectively. SWISS: Q68DA7 Gene ID: 342184 |
| 产品图片 |  The purity of the protein is greater than 83% as determined by reducing SDS-PAGE. |
