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重组人TNFRSF14蛋白
产品名称:
重组人TNFRSF14蛋白
英文名称:
Recombinant human TNFRSF14 protein, C-His (HEK293)
产品类别:
蛋白多肽
产品编号:
bs-43562P
保存条件:
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw
[价格]
规格 价格 库存
100ug ¥ 4880.00 10
500ug ¥ 15800.00 10

产品详情

产品编号bs-43562P
英文名称Recombinant human TNFRSF14 protein, C-His (HEK293)
中文名称重组人TNFRSF14蛋白
别????名HVEM; Tumor necrosis factor receptor superfamily member 14; HveA1; Tumor necrosis factor receptor-like 2; TR21; CD270; Herpesvirus entry mediator A; TNR14_HUMAN. Similar to Tumor necrosis factor ligand superfamily member 14 (CD258 antigen); CD258; CD258 antigen; CD40 like protein precursor; Herpesvirus entry mediator; Herpesvirus entry mediator ligand; HVEA; HVEM L; HVEML; LIGHT; LIGHTR; TNFSF 14; TR2; UNQ329/PRO509??
理论分子量18.4kDa
性????状Lyophilized or Liquid
浓????度>0.72mg/ml
物????种Human
序????列39-202/283
纯????度>90% as determined by SDS-PAGE
纯化方法AC
内毒素Not analyzed
表达系统HEK293 cell
活性Not tested
标签C-His
缓?冲?液PBS (pH=7.4)
保存条件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍TNFRSF14 is a type I membrane protein belonging to the TNF receptor superfamily. This receptor mediates herpes virus entry into cells during infection. TNFRSF14 is able to inhibit the proliferation, activation, and cytokine production of T cells. It has an extracellular domain containing several cysteine-rich repeats and a short cytoplasmic region containing a TRAF (TNF receptor-associated factor) interaction domain. The extracellular domain of TNFRSF14 interacts with the herpes simplex virus envelope glycoprotein D. TNFRSF14 binds two cellular ligands: lymphotoxin alpha and LIGHT. LIGHT is a transmembrane protein expressed and shed from the surface of activated T cells, exhibits inducible expression, and competes with HSV glycoprotein D for HVEM, a receptor expressed by T lymphocytes. The LIGHT:TNFRSF14 interaction controls immune response functions by cell death induction as well as cell activation. TNFRSF14 is expressed by peripheral blood T cells, B cells, monocytes and in various tissues enriched in lymphoid cells.

SWISS:
Q92956

Gene ID:
8764

产品图片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.

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