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重组丝氨酸苏氨酸激酶1受体相互作用蛋白
产品名称:
重组丝氨酸苏氨酸激酶1受体相互作用蛋白
英文名称:
Recombinant human RIPK1 protein, N-His
产品类别:
蛋白多肽
产品编号:
bs-42114P
保存条件:
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw
[价格]
规格 价格 库存
100ug ¥ 2980.00 10
500ug ¥ 9500.00 10

产品详情

产品编号bs-42114P
英文名称Recombinant human RIPK1 protein, N-His
中文名称重组丝氨酸苏氨酸激酶1受体相互作用蛋白
别????名Cell death protein RIP; Receptor (TNFRSF) interacting serine threonine kinase 1; Receptor interacting protein; Receptor interacting serine threonine protein kinase 1; Receptor TNFRSF interacting serine threonine kinase 1; Receptor-interacting protein 1; Receptor-interacting serine/threonine-protein kinase 1; Rinp; RIP; Rip-1; RIPK 1; RIPK-1; RIPK1_HUMAN; Serine threonine protein kinase RIP; Serine/threonine-protein kinase RIP.??
理论分子量28.7kDa
性????状Lyophilized or Liquid
浓????度>1mg/ml
物????种Human
纯????度>90% as determined by SDS-PAGE
内毒素Not analyzed
表达系统E.coli
活性Not tested
标签C-His
缓?冲?液20mM Tris (pH=8.0) with 8M Urea
保存条件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍Essential adapter molecule for the activation of NF-kappa-B. Following different upstream signals (binding of inflammatory cytokines, stimulation of pathogen recognition receptors, or DNA damage), particular RIPK1-containing complexes are formed, initiating a limited number of cellular responses. Upon TNFA stimulation RIPK1 is recruited to a TRADD-TRAF complex initiated by TNFR1 trimerization. There, it is ubiquitinated via 'Lys-63'-link chains, inducing its association with the IKK complex, and its activation through NEMO binding of polyubiquitin chains.

SWISS:
Q13546

Gene ID:
8737

产品图片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.

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