规格 | 价格 | 库存 |
---|---|---|
100ug | ¥ 4880.00 | 10 |
500ug | ¥ 15800.00 | 10 |
产品编号 | bs-41335P |
英文名称 | Recombinant human LAMP1 protein, His (HEK293) |
中文名称 | 重组人溶酶体相关膜蛋白1 |
别????名 | CD107 antigen like family member A; CD107 antigen-like family member A; CD107a; CD107a antigen; LAMP 1; LAMP-1; LAMP1_HUMAN; LAMPA; LGP120; lgpA; Lysosomal membrane glycoprotein 120KD; Lysosomal Associated Membrane Protein 1; Lysosome associated membrane glycoprotein 1; Lysosome-associated membrane glycoprotein 1; Lysosome-associated membrane glycoprotein 1; Lysosome-associated membrane protein 1;?? |
理论分子量 | 39.7kDa |
性????状 | Lyophilized or Liquid |
物????种 | Human |
序????列 | 29-382/417 |
纯????度 | >90% as determined by SDS-PAGE |
纯化方法 | AC |
内毒素 | Not analyzed |
表达系统 | HEK293 cell |
活性 | Not tested |
标签 | C-His |
保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 | Lysosome associated membrane protein (LAMP1), also known as lgp120 or lgpA, is a type 1 integral membrane protein that is transported from trans Golgi networks to endosomes and then lysosomes. Upon cell activation, LAMP1 transfer to the plasma membrane is dependent on a carboxyl terminal tyrosine based motif (YXXI). Perturbation in the spacing between the tyrosine based motif relative to the membrane abolishes lysosome localization of LAMP1. This mutant protein then cycles between the plasma membrane and the endosome. Cell surface LAMP1 and LAMP2 have been shown to promote adhesion of human peripheral blood mononuclear cells (PBMC) to vascular endothelium, therefore they are possibly involved in the adhesion of PBMCs to the site of inflammation. SWISS: P11279 Gene ID: 3916 |
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