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重组抗CRISPR-Cas9蛋白
产品名称:
重组抗CRISPR-Cas9蛋白
英文名称:
Recombinant CRISPR-Cas9 protein, C-His
产品类别:
蛋白多肽
产品编号:
bs-41498P
保存条件:
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw
[价格]
规格 价格 库存
100ug ¥ 3980.00 10
500ug ¥ 12800.00 10

产品详情

产品编号bs-41498P
英文名称Recombinant CRISPR-Cas9 protein, C-His
中文名称重组抗CRISPR-Cas9蛋白
别????名Cas9 ; CRISPR-associated endonuclease Cas9/Csn1 ; CRISPR-Cas9/Csn1 ; csn1 ; SpyCas9.??
理论分子量164kDa
性????状Lyophilized or Liquid
浓????度0.3mg/ml
物????种Streptococcus pyogenes
序????列2-1368/1368
纯????度> 90% as determined by SDS-PAGE
表达系统E.coli
活性Not tested
标签C-His
缓?冲?液PBS (pH=7.4)
保存条件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA) (Probable). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9/crRNA/tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer. The target strand not complementary to crRNA is first cut endonucleolytically, then trimmed by 3'-5' exonucleolytically. DNA-binding requires protein and both RNA species. Cas9 probably recognizes a short motif in the CRISPR repeat sequences (the PAM or protospacer adjacent motif) to help distinguish self versus nonself.

SWISS:
Q99ZW2

Gene ID:
901176

产品图片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.

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