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重组人髓鞘少树突胶质细胞糖蛋白
产品名称:
重组人髓鞘少树突胶质细胞糖蛋白
英文名称:
Recombinant human MOG protein, N-Trx-His
产品类别:
蛋白多肽
产品编号:
bs-41445P
保存条件:
Shipped at 4℃. Store at -20 °C for one year. Avoid
[价格]
规格 价格 库存
100ug ¥ 2980.00 10
500ug ¥ 9500.00 10

产品详情

产品编号bs-41445P
英文名称Recombinant human MOG protein, N-Trx-His
中文名称重组人髓鞘少树突胶质细胞糖蛋白
别????名MOG(35-55); myelin oligo-dendrocyte glycoprotein-MOG; MGC26137; MOG alpha 6; MOG; MOGIG2; Myelin oligodendrocyte glycoprotein; Myelin-oligodendrocyte glycoprotein; MOG_HUMAN; Recombinant human MOG protein, N-Trx-His??
理论分子量35kDa
性????状Lyophilized or Liquid
浓????度>0.5 mg/ml
物????种Human
序????列30-149/247
纯????度>90% as determined by SDS-PAGE
纯化方法AC
内毒素Not analyzed
表达系统E.coli
活性Not tested
标签N-Trx-His
保存条件Shipped at 4℃. Store at -20 °C for one year. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍Myelin oligodendrocyte glycoprotein (MOG) is a key CNS-specific autoantigen for primary demyelination in multiple sclerosis. Although the disease-inducing role of MOG has been established, its precise function in the CNS remains obscure. MOG is a type I integral membrane protein possessing a single extracellular Ig variable domain (Ig-V) (3, 13, 14). The amino acid sequence of MOG is highly conserved among animal species (>90%), indicative of an important biological function. MOG is specifically expressed in the CNS on the outermost lamellae of the myelin sheath as well as the cell body and processes of oligodendrocytes. The developmentally late expression of MOG correlates with the later stages of myelinogenesis, suggesting that MOG has a role in the completion, compaction, and/or maintenance of myelin, further suggesting that MOG has an adhesive function within the CNS . Consistent with MOG's possible adhesive role in the CNS, a homodimeric form of MOG has not only been observed after isolation from the CNS but has additionally been observed in situ.

SWISS:
Q61885

Gene ID:
4340

产品图片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.

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