产品编号 | bs-41394P |
英文名称 | Recombinant mouse ABCG5 protein, N-GST & C-His |
中文名称 | 重组小鼠三磷酸腺苷结合转运蛋白G超家族成员5 |
别????名 | ABCG5; ABCG5_HUMAN; ATP binding cassette sub family G (WHITE) member 5 (sterolin 1); ATP binding cassette sub family G member 5; ATP-binding cassette sub-family G member 5; Sterolin 1; Sterolin-1; STSL; Recombinant mouse ABCG5 protein, N-GST & C-His?? |
理论分子量 | 37kDa |
检测分子量 | 33 kDa |
性????状 | Lyophilized or Liquid |
浓????度 | >0.5 mg/ml |
物????种 | Mouse |
序????列 | 1-85/652 |
纯????度 | >90% as determined by SDS-PAGE |
纯化方法 | AC |
内毒素 | Not analyzed |
表达系统 | E.coli |
活性 | Not tested |
标签 | N-GST & C-His |
缓?冲?液 | 4 M Urea (pH=9.2) with 1 mM DDT |
保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols. It is expressed in a tissue-specific manner in the liver, colon, and intestine. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8. Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008].
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产品图片 | The purity of the protein is greater than 78% as determined by reducing SDS-PAGE. |
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