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重组人丝氨酸蛋白激酶Sgk3蛋白
产品名称:
重组人丝氨酸蛋白激酶Sgk3蛋白
英文名称:
Recombinant human SGK3 protein
产品类别:
蛋白多肽
产品编号:
bs-41362P
保存条件:
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw
[价格]
规格 价格 库存
100ug ¥ 2980.00 10
500ug ¥ 9500.00 10

产品详情

产品编号bs-41362P
英文名称Recombinant human SGK3 protein
中文名称重组人丝氨酸蛋白激酶Sgk3蛋白
别????名CISK; Cytokine independent survival kinase; Serine/threonine protein kinase Sgk3; Serine/threonine-protein kinase Sgk3; Serum/glucocorticoid regulated kinase 3; Serum/glucocorticoid regulated kinase family member 3; Serum/glucocorticoid regulated kinase like; Serum/glucocorticoid-regulated kinase 3; Serum/glucocorticoid-regulated kinase-like; SGK 2; SGK 3; SGK2; Sgk3; SGK3_HUMAN; SGKL.??
理论分子量44.8kDa
检测分子量42 kDa
性????状Lyophilized or Liquid
浓????度>0.5 mg/ml
序????列160-496/496
纯????度>90% by SDSD-PAGE
内毒素Not analyzed
活性No tested
标签N-His Tag
缓?冲?液PBS pH7.5
保存条件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍Serine/threonine-protein kinase Sgk3 (SGK3), also designated serum/glucocorticoid regulated kinase 3, belongs to the Ser/Thr protein kinase family of proteins. The serum- and glucocorticoid-regulated kinase proteins are closely related to the Akt protein family. SGK1, a homolog of SGK3, activates ion channels, in particular potassium (K+) channels. SGK2 and SGK3 have been found to also be involved in this activation process, making all three of these proteins important regulators for cell proliferation, epithelial transport and neuromuscular excitability. SGK3 acts as a mediator of IL-3 dependent survival signals in the cell. It localizes to the early endosome and in vesicle-like structures. SGK3 is a widely expressed protein, but it is primarily detected in kidney, liver, pancreas, brain and heart. Phosphorylation of SGK3 at residue Ser 486 leads to an increase in SGK3 activation.

SWISS:
Q96BR1

Gene ID:
100533105

产品图片
The purity of the protein is greater than 24% as determined by reducing SDS-PAGE.

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