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重组人丝氨酸蛋白酶10
产品名称:
重组人丝氨酸蛋白酶10
英文名称:
Recombinant human TMPRSS2 protein
产品类别:
蛋白多肽
产品编号:
bs-41361P
保存条件:
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw
[价格]
规格 价格 库存
100ug ¥ 2980.00 10
500ug ¥ 9500.00 10

产品详情

产品编号bs-41361P
英文名称Recombinant human TMPRSS2 protein
中文名称重组人丝氨酸蛋白酶10
别????名Epitheliasin; PRSS10; Serine protease 10; TMPRSS2; TMPRSS2 ERG FUSION GENE, INCLUDED; TMPRSS2 ETV1 FUSION GENE, INCLUDED; TMPS2_HUMAN; Transmembrane protease serine 2 catalytic chain; Transmembrane protease, serine 2; Transmembrane protease, serine 2, EC 3.4.219; Transmembrane protease, serine 2, EC 3.4.219; D16Ertd61e.??
理论分子量44.8kDa
检测分子量40 kDa
性????状Lyophilized or Liquid
浓????度>0.5 mg/ml
序????列108-492/492
纯????度>90% by SDSD-PAGE
内毒素Not analyzed
活性No tested
标签N-His Tag
缓?冲?液PBS pH7.5
保存条件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍Extracellular proteases mediate the digestion of neighboring extracellular matrix components in initial tumor growth, allow desquamation of tumor cells into the surrounding environment, provide the basis for invasion of basement membranes in targeted metastatic organs and are required for release and activation of many growth and angiogenic factors (1,2). The TMPRSS2 gene encodes a 492 amino acid multimeric serine protease, which is mainly expressed in the mouse prostate and kidney, and is also expressed in the human small intestine, prostate, colon, stomach and salivary gland (3,4). TMPRSS2 contains several domains, including a serine protease domain of the S1 family, a scavenger receptor cysteine-rich domain of group A, an LDL receptor class A domain and a transmembrane domain (3). TMPRSS2 is expressed as a full length form and a cleaved protease domain (5) and its expression is increased by androgenic hormones. TMPRSS2 is also expressed in prostate carcinoma, suggesting that it may play a role in prostate carcinogenesis (6).

SWISS:
O15393

Gene ID:
7113

产品图片
The purity of the protein is greater than 86% as determined by reducing SDS-PAGE.

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