产品编号 | bs-41373P |
英文名称 | Recombinant mouse GAPDH protein, His |
中文名称 | 重组小鼠3-磷酸甘油醛脱氢酶蛋白 |
别????名 | Glyceraldehyde-3-phosphate dehydrogenase; Recombinant mouse GAPDH protein, His?? |
理论分子量 | 35.8kDa |
检测分子量 | 38 kDa |
性????状 | Lyophilized or Liquid |
浓????度 | >0.5 mg/ml |
物????种 | Mouse |
序????列 | 1-333/333 |
纯????度 | >90% as determined by SDS-PAGE |
纯化方法 | AC |
内毒素 | Not analyzed |
表达系统 | E.coli |
活性 | Not tested |
标签 | His |
缓?冲?液 | 20 mM Tris-HCl (pH=8.0) with 200 mM Arg |
保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 | Glyceraldehyde-3-phosphate dehydrogenase (GAPDH) is well known as one of the key enzymes involved in glycolysis. It catalyzes an important energy-yielding step in carbohydrate metabolism, thereversible oxidative phosphorylation of glyceraldehyde-3-phosphatein the presence of inorganic phosphate and nicotinamide adenine dinucleotide (NAD). Recent evidence suggests that it also is involved in a number of cellular processes such as membrane fusion, phosphotransferase activity, DNA replication and repair, and nuclear RNA export (1). GAPDH has also been implicated in playing a role in different pathologies such as cancer progression, apoptosis, and neuronal diseases such as Alzheimer’s and Huntington’s disease (2). GAPDH is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots.
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产品图片 | The purity of the protein is greater than 90% as determined by reducing SDS-PAGE. |
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