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重组胆固醇25羟化酶蛋白
产品名称:
重组胆固醇25羟化酶蛋白
英文名称:
Recombinant human CH25H protein, His
产品类别:
蛋白多肽
产品编号:
bs-41322P
保存条件:
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw
[价格]
规格 价格 库存
100ug ¥ 3980.00 10
500ug ¥ 12800.00 10

产品详情

产品编号bs-41322P
英文名称Recombinant human CH25H protein, His
中文名称重组胆固醇25羟化酶蛋白
别????名C25H; CH25H; Cholesterol 25 hydroxylase; Cholesterol 25 monooxygenase; EC 1.14.99.38; EC=1.14.99.38; h25OH; CH25H_HUMAN; Recombinant human CH25H protein, His??
理论分子量14kDa
检测分子量14 kDa
性????状Lyophilized or Liquid
浓????度>0.5 mg/ml
物????种Human
序????列140-272/272
纯????度>95% as determined by SDS-PAGE
纯化方法AC
内毒素Not analyzed
表达系统E.coli
活性Not tested
标签His
缓?冲?液4 M Urea (pH=9.0) with 300 mM NaCl
保存条件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍CH25H (Cholesterol 25-hydroxylase), also known as h25OH, is a 272 amino acid endoplasmic membrane protein that belongs to the sterol desaturase family. CH25H contains clusters of histidine residues essential for catalytic activity and is involved in cholesterol and lipid metabolism. CH25H catalyzes the formation of 25-hydroxycholesterol from cholesterol leading to the repression of cholesterol biosynthetic enzymes. CH25H regulates lipid metabolism by synthesizing a corepressor that blocks sterol regulatory element binding protein (SREBP) processing. CH25H utilizes diiron cofactors to catalyze the hydroxylation of hydrophobic substrates.

产品图片
The purity of the protein is greater than 80% as determined by reducing SDS-PAGE.

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