规格 | 价格 | 库存 |
---|---|---|
100ug | ¥ 2980.00 | 10 |
500ug | ¥ 9680.00 | 10 |
产品编号 | bs-49102P |
英文名称 | Recombinant HPV16 E6 protein, DsbC & His |
中文名称 | 重组人类乳头状瘤病毒16-E6蛋白 |
别????名 | E6; HPV16 E6 protein; Human Papilloma Virus; Human papillomavirus type 16 E6; Human papillomavirus type 16; Protein E6; E6 protein; HPV16 E6; HPV16-E6; VE6_HPV16; Recombinant HPV16 E6 protein, DsbC & His?? |
理论分子量 | 49.5kDa |
检测分子量 | 50 kDa |
性????状 | Lyophilized or Liquid |
浓????度 | >0.5 mg/ml |
物????种 | HPV |
序????列 | 1-158/158 |
纯????度 | >95% as determined by SDS-PAGE |
纯化方法 | AC |
内毒素 | Not analyzed |
表达系统 | E.coli |
活性 | Not tested |
标签 | DsbC & His |
缓?冲?液 | 20 mM Tris-HCl (pH=8.0) |
保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 | Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types. Approximately 90% of cervical cancers contain HPV DNA of the high risk types. Mutational analysis have shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function. The specific interactions of the E6 and E7 proteins with p53 and pRB, respectively, correlate with HPV high and low risk classifications. The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro. SWISS: P03126 Gene ID: 1489078 |
产品图片 | |