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重组人类乳头状瘤病毒16-E6蛋白
产品名称:
重组人类乳头状瘤病毒16-E6蛋白
英文名称:
Recombinant HPV16 E6 protein, DsbC & His
产品类别:
蛋白多肽
产品编号:
bs-49102P
保存条件:
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw
[价格]
规格 价格 库存
100ug ¥ 2980.00 10
500ug ¥ 9680.00 10

产品详情

产品编号bs-49102P
英文名称Recombinant HPV16 E6 protein, DsbC & His
中文名称重组人类乳头状瘤病毒16-E6蛋白
别????名E6; HPV16 E6 protein; Human Papilloma Virus; Human papillomavirus type 16 E6; Human papillomavirus type 16; Protein E6; E6 protein; HPV16 E6; HPV16-E6; VE6_HPV16; Recombinant HPV16 E6 protein, DsbC & His??
理论分子量49.5kDa
检测分子量50 kDa
性????状Lyophilized or Liquid
浓????度>0.5 mg/ml
物????种HPV
序????列1-158/158
纯????度>95% as determined by SDS-PAGE
纯化方法AC
内毒素Not analyzed
表达系统E.coli
活性Not tested
标签DsbC & His
缓?冲?液20 mM Tris-HCl (pH=8.0)
保存条件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍Human papilloma viruses (HPVs) can be classified as either high risk or low risk according to their association with cancer. HPV16 and HPV18 are the most common of the high risk group while HPV6 and HPV11 are among the low risk types. Approximately 90% of cervical cancers contain HPV DNA of the high risk types. Mutational analysis have shown that the E6 and E7 genes of the high risk HPVs are necessary and sufficient for HPV transforming function. The specific interactions of the E6 and E7 proteins with p53 and pRB, respectively, correlate with HPV high and low risk classifications. The high risk HPV E7 proteins bind to pRB with a higher affinity than do the low risk HPV proteins, and only the high risk HPV E6 proteins form detectable complexes with p53 in vitro.

SWISS:
P03126

Gene ID:
1489078

产品图片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.

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