规格 | 价格 | 库存 |
---|---|---|
10ug | ¥ 2080.00 | 10 |
50ug | ¥ 6800.00 | 10 |
500ug | ¥ 28000.00 | 10 |
产品编号 | bs-48016P |
英文名称 | Recombinant human BMP-4 protein (Active, HEK293) |
中文名称 | 重组人骨形态发生蛋白-4 (活性的, Tag free) |
别????名 | rhBMP-4; BMP 4; BMP2B; BMP2B1; Bone morphogenetic protein 4; DVR4; ZYME; BMP4_HUMAN; BMP-4; Bone morphogenetic protein 2B; BMP-2B. ;Recombinant human BMP-4 protein (Active, HEK293)??人骨形态发生蛋白-4重组蛋白; 重组人骨形态发生蛋白-4; 人重组骨形态发生蛋白-4; 重组人BMP4; |
检测分子量 | 34-40 kDa |
性????状 | Lyophilized powder |
浓????度 | >0.5 mg/ml |
物????种 | Human |
序????列 | 293-408/408 |
纯????度 | >95% as determined by SDS-PAGE |
纯化方法 | AC |
内毒素 | <0.5 EU/μg as determined by LAL. |
表达系统 | HEK293 cell |
活性 | Yes |
标签 | Tag free |
缓?冲?液 | Lyophilized from 0.22 um filtered solution in PBS (pH=7.4) with 5 mM DTT. Normally 5% trehalose is added as protectant before Lyophilization. |
保存条件 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after reconstitution. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 | Bone morphogenetic protein 4 (BMP-4) is a member of transforming growth factor β family that includes more than 20 structurally related bone growth factors. BMP-4 is widely expressed from early embryogenesis through adulthood. It plays an important role in cartilage and bone formation, mesoderm induction, tooth development, limb formation and fracture repair. Mature human BMP-4 is a 116 amino acids glycoprotein and normally found as a homodimer. Dimerization is facilitated by a disulfide bridge formed between the monomer, which contains three intrachain disulfide bridges arranged in a cystine knot motif. BMP-4 signals through tetrameric complexes composed of type I (primarily Activin RIA or BMPRIA) and type II (primarily Activin RIIA or BMPRII) receptors. The bioavailability of BMP-4 is regulated by its interaction with multiple proteins and glycosaminoglycans. This recombinant human BMP-4 is produced by human cells.(Tag free) Biological activity: The activity was measured by its ability to induce alkaline phosphatase production in the ATDC-5 cell line (Mouse chondrogenic cell line). Reconstitution: Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin. SWISS: P12644 Gene ID: 652 |
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