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重组人骨形态发生蛋白-4 (活性的, Tag free)
产品名称:
重组人骨形态发生蛋白-4 (活性的, Tag free)
英文名称:
Recombinant human BMP-4 protein (Active, HEK293)
产品类别:
蛋白多肽
产品编号:
bs-48016P
保存条件:
Use a manual defrost freezer and avoid repeated fr
[价格]
规格 价格 库存
10ug ¥ 2080.00 10
50ug ¥ 6800.00 10
500ug ¥ 28000.00 10

产品详情

产品编号bs-48016P
英文名称Recombinant human BMP-4 protein (Active, HEK293)
中文名称重组人骨形态发生蛋白-4 (活性的, Tag free)
别????名rhBMP-4; BMP 4; BMP2B; BMP2B1; Bone morphogenetic protein 4; DVR4; ZYME; BMP4_HUMAN; BMP-4; Bone morphogenetic protein 2B; BMP-2B. ;Recombinant human BMP-4 protein (Active, HEK293)??人骨形态发生蛋白-4重组蛋白; 重组人骨形态发生蛋白-4; 人重组骨形态发生蛋白-4; 重组人BMP4;
检测分子量34-40 kDa
性????状Lyophilized powder
浓????度>0.5 mg/ml
物????种Human
序????列293-408/408
纯????度>95% as determined by SDS-PAGE
纯化方法AC
内毒素<0.5 EU/μg as determined by LAL.
表达系统HEK293 cell
活性Yes
标签Tag free
缓?冲?液Lyophilized from 0.22 um filtered solution in PBS (pH=7.4) with 5 mM DTT. Normally 5% trehalose is added as protectant before Lyophilization.
保存条件Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after reconstitution.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍Bone morphogenetic protein 4 (BMP-4) is a member of transforming growth factor β family that includes more than 20 structurally related bone growth factors. BMP-4 is widely expressed from early embryogenesis through adulthood. It plays an important role in cartilage and bone formation, mesoderm induction, tooth development, limb formation and fracture repair. Mature human BMP-4 is a 116 amino acids glycoprotein and normally found as a homodimer. Dimerization is facilitated by a disulfide bridge formed between the monomer, which contains three intrachain disulfide bridges arranged in a cystine knot motif. BMP-4 signals through tetrameric complexes composed of type I (primarily Activin RIA or BMPRIA) and type II (primarily Activin RIIA or BMPRII) receptors. The bioavailability of BMP-4 is regulated by its interaction with multiple proteins and glycosaminoglycans.

This recombinant human BMP-4 is produced by human cells.(Tag free)

Biological activity:
The activity was measured by its ability to induce alkaline phosphatase production in the ATDC-5 cell line (Mouse chondrogenic cell line).

Reconstitution:
Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.



SWISS:
P12644

Gene ID:
652

产品图片
The purity of the protein is greater than 95% as determined by non reduced and reduced SDS-PAGE

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