规格 | 价格 | 库存 |
---|---|---|
10ug | ¥ 2680.00 | 10 |
50ug | ¥ 8800.00 | 10 |
500ug | ¥ 58000.00 | 10 |
产品编号 | bs-48008P |
英文名称 | Recombinant human IL-28A protein (Active, HEK293) |
中文名称 | 重组人白介素28A (活性的, Tag free) |
别????名 | rhIL-28A; Interleukin 28/Interferon lambda-2; Interleukin 28A; IL28A; IFNL2; IL-28A; rhIL-28A; EG330496; Ifnl2; IFNL2_HUMAN. ;Recombinant human IL-28A protein (Active, HEK293)??人白介素28A 重组蛋白; 人白细胞介素28A ; 重组人白介素28A; |
理论分子量 | 24kDa |
检测分子量 | 17-38 kDa |
性????状 | Lyophilized powder |
浓????度 | >0.5 mg/ml |
物????种 | Human |
序????列 | 26-200/200 |
纯????度 | >95% as determined by SDS-PAGE |
纯化方法 | AC |
内毒素 | <0.5 EU/μg as determined by LAL. |
表达系统 | HEK293 cell |
活性 | Yes |
标签 | Tag free |
缓?冲?液 | Lyophilized from 0.22 um filtered solution in PBS (pH=7.4) with 5 mM DTT. Normally 5% trehalose is added as protectant before Lyophilization. |
保存条件 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after reconstitution. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 | IL-28A, also named interferon λ2 (IFNλ2), belongs to the type III interferon protein family, which is distinct from the type I IFNs. IL-28A is induced by virus infection or double stranded RNA. IL-28A acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. IL-28A has antiviral, antitumour and immunomodulatory activities, plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. This recombinant human IL-28A is produced by human cells.(Tag free) Biological activity: The activity was measured by its anti-virus function in A549 cells (human lung adenocarcinoma epithelial cell line) infected with encephalomyocarditis (EMC) virus. Reconstitution: Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin. SWISS: Q8IZJ0 Gene ID: 282616 |
产品图片 | |