规格 | 价格 | 库存 |
---|---|---|
10ug | ¥ 2680.00 | 10 |
50ug | ¥ 8800.00 | 10 |
产品编号 | bs-48007P |
英文名称 | Recombinant human IL-23 protein (Active, HEK293) |
中文名称 | 重组人白介素23 (活性的, Tag free) |
别????名 | rhIL-23; IL 23; IL 23A; IL23P19; Interleukin 23 alpha subunit p19; JKA3 induced upon T cell activation; P19; SGRF; IL-23 subunit alpha; IL-23-A; IL-23p19; IL23; Il23a; IL23A_HUMAN; Interleukin 23 p19 subunit; Interleukin-23 subunit alpha; Interleukin-23 subunit p19; JKA3 induced upon T cell activation; MGC79388; P19. ;Recombinant human IL-23 protein (Active, HEK293)??人白介素23 重组蛋白; 人白细胞介素23 ; 重组人白介素23; |
理论分子量 | 55kDa |
检测分子量 | 60 kDa |
性????状 | Lyophilized powder |
浓????度 | >0.5 mg/ml |
物????种 | Human |
序????列 | 23-189/189 |
纯????度 | >95% as determined by SDS-PAGE |
纯化方法 | AC |
内毒素 | <0.5 EU/μg as determined by LAL. |
表达系统 | HEK293 cell |
活性 | Yes |
标签 | Tag free |
缓?冲?液 | Lyophilized from 0.22 um filtered solution in PBS (pH=7.4) with 5 mM DTT. Normally 5% trehalose is added as protectant before Lyophilization. |
保存条件 | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after reconstitution. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 | IL-23 is a heterodimeric cytokine composed of two subunits: a unique p19 subunit, and a p40 subunit that is shared with IL-12. IL-23 is secreted by activated dendritic cells and macrophages. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T cells and promotes production of proinflammatory cytokines, such as IFNγ and IL-17. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis. This recombinant human IL-23 is produced by human cells.(Tag free) Biological activity: The activity was measured by its ability to induce the IL-17 expression in murine splenocytes. Reconstitution: Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin. SWISS: Q9NPF7 Gene ID: 51561 |
产品图片 | |