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重组人肿瘤坏死因子α (活性的, Tag free)
产品名称:
重组人肿瘤坏死因子α (活性的, Tag free)
英文名称:
Recombinant human TNF-Alpha protein (Active, HEK293)
产品类别:
蛋白多肽
产品编号:
bs-48004P
保存条件:
Use a manual defrost freezer and avoid repeated fr
[价格]
规格 价格 库存
10ug ¥ 880.00 10
50ug ¥ 1980.00 10
500ug ¥ 8800.00 10

产品详情

产品编号bs-48004P
英文名称Recombinant human TNF-Alpha protein (Active, HEK293)
中文名称重组人肿瘤坏死因子α (活性的, Tag free)
别????名Tumor necrosis factor-α; APC1; Cachectin; DIF; Differentiation inducing factor; Macrophage cytotoxic factor; MCF; Necrosin; TNF a ; TNF alpha; TNFalpha; TNF; TNF Macrophage Derived; TNF Monocyte Derived; TNF Superfamily Member 2; TNFA; TNFSF2; Tumor necrosis factor ligand superfamily member 2; Tumor Necrosis Factor Precurso; Tumour Necrosis Factor Alpha. ;Recombinant human TNF-Alpha protein (Active, HEK293)??肿瘤坏死因子α重组蛋白; 肿瘤坏死因子α; 重组人肿瘤坏死因子α; 重组人TNF α;
理论分子量17kDa
检测分子量17 kDa
性????状Lyophilized powder
浓????度>0.5 mg/ml
物????种Human
序????列77-233/233
纯????度>95% as determined by SDS-PAGE
纯化方法AC
内毒素<0.5 EU/μg as determined by LAL.
表达系统HEK293 cell
活性Yes
标签Tag free
缓?冲?液Lyophilized from 0.22 um filtered solution in PBS (pH=7.4) with 5 mM DTT. Normally 5% trehalose is added as protectant before Lyophilization.
保存条件Use a manual defrost freezer and avoid repeated freeze-thaw cycles. In general: 12 months from date of receipt, -20 to -80℃ as supplied. 1 month, 2 to 8℃ under sterile conditions after reconstitution. 3 months, -20 to -80℃ under sterile conditions after reconstitution.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍Tumor necrosis factor alpha (TNFα) is an EGF related polypeptide growth factor that signals through the TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and also produced by monocytes, keratinocytes, and various tumor cells. TNFα stimulates the proliferation of a wide range of epidermal and epithelial cells. TNFα is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia. Under certain conditions it can stimulate cell proliferation and induce cell differentiation, impair regulatory T cells (Treg) function in individuals with rheumatoid arthritis via FOXP3 dephosphorylation.

This recombinant human TNF alpha (Glycosylated homotrimer) is produced by human cells.(Tag free)

Biological activity:
The activity was measured by the cytotoxicity in L-929 cell in the presence of actinomycin D.

Reconstitution:
Briefly centrifuge the vial before opening. It is recommended to reconstitute the protein in sterile PBS containing 0.1% endotoxin-free recombinant human serum albumin.



SWISS:
P01375

Gene ID:
7124

产品图片
The purity of the protein is greater than 95% as determined by non reduced and reduced SDS-PAGE.

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