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重组人色素上皮源性因子蛋白
产品名称:
重组人色素上皮源性因子蛋白
英文名称:
Recombinant human PEDF protein, His
产品类别:
蛋白多肽
产品编号:
bs-41083P
保存条件:
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw
[价格]
规格 价格 库存
100ug ¥ 3980.00 10
500ug ¥ 12800.00 10

产品详情

产品编号bs-41083P
英文名称Recombinant human PEDF protein, His
中文名称重组人色素上皮源性因子蛋白
别????名pigment epithelium-derived factor; Serpin-F1; Stromal cell-derived factor 3; SDF-3; Caspin; Alpha 2 antiplasmin; EPC 1; EPC1; PIG 35; PIG35; Pigment epithelium derived factor; Proliferation inducing protein 35; SERPIN F1; Serpin peptidase inhibitor clade F member 1; SERPINF 1; SERPINF1; PEDF_HUMAN; Recombinant human PEDF protein, His??
理论分子量45.2kDa
检测分子量55 kDa
性????状Lyophilized or Liquid
浓????度>0.5 mg/ml
物????种Human
序????列20-418/418
纯????度>95% as determined by SDS-PAGE
纯化方法AC
内毒素Not analyzed
表达系统E.coli
活性Not tested
标签His
缓?冲?液20 mM Tris-HCl (pH=8.0) with 8 M Urea
保存条件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍Pigment epithelium derived factor, originally identified in conditioned medium of cultured human fetal retinal pigment epithelial (RPE) cells, is a neurotrophic protein that induces extensive neuronal differentiation in human Y79 retinoblastoma cells, a neoplastic counterpart of normal retinoblasts. It has been suggested that PEDF is synthesized by RPE cells and secreted into the retina interphotoreceptor matrix where it may influence development/differentiation of the neural retina. PEDF is a potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity. The PEDF gene is a member of the serpin gene family. Serpins are a group of serine protease inhibitors, some of which have also been reported to exhibit neurotrophic activity.

SWISS:
P97298

Gene ID:
5176

产品图片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.

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