规格 | 价格 | 库存 |
---|---|---|
100ug | ¥ 3980.00 | 10 |
500ug | ¥ 12800.00 | 10 |
产品编号 | bs-41117P |
英文名称 | Recombinant human PD-1 protein, His |
中文名称 | 重组人程序性死亡1(CD279)蛋白 |
别????名 | CD279; CD279 antigen; hPD 1; hPD l; hPD-1; hSLE1; PD 1; PD1; PDCD 1; PDCD1; PDCD1_HUMAN; Programmed cell death 1; Programmed cell death protein 1; Protein PD 1; Protein PD-1; SLEB2; Systemic lupus erythematosus susceptibility 2; Recombinant human PD-1 protein, His?? |
理论分子量 | 17.57kDa |
检测分子量 | 17 kDa |
性????状 | Lyophilized or Liquid |
浓????度 | >0.5 mg/ml |
物????种 | Human |
序????列 | 21-170/288 |
纯????度 | >95% as determined by SDS-PAGE |
纯化方法 | AC |
内毒素 | Not analyzed |
表达系统 | E.coli |
活性 | Not tested |
标签 | His |
缓?冲?液 | 20 mM Tris-HCl (pH=9.0) with 8 M Urea |
保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
产品介绍 | This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. CD279 is an immunoglobulin superfamily member, also known as Programmed Cell Death 1. Programmed Cell Death 1 is expressed on a subset of CD4-CD8 thymocytes, and on activated T and B cells. Programmed Cell Death 1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The Programmed Cell Death 1 ligands, PDL1 (also known as B7H1) and PDL2 (B7DC), are members of the B7 immunoglobulin superfamily. SWISS: Q15116 Gene ID: 5133 |
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