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重组人程序性死亡1(CD279)蛋白
产品名称:
重组人程序性死亡1(CD279)蛋白
英文名称:
Recombinant human PD-1 protein, His
产品类别:
蛋白多肽
产品编号:
bs-41117P
保存条件:
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw
[价格]
规格 价格 库存
100ug ¥ 3980.00 10
500ug ¥ 12800.00 10

产品详情

产品编号bs-41117P
英文名称Recombinant human PD-1 protein, His
中文名称重组人程序性死亡1(CD279)蛋白
别????名CD279; CD279 antigen; hPD 1; hPD l; hPD-1; hSLE1; PD 1; PD1; PDCD 1; PDCD1; PDCD1_HUMAN; Programmed cell death 1; Programmed cell death protein 1; Protein PD 1; Protein PD-1; SLEB2; Systemic lupus erythematosus susceptibility 2; Recombinant human PD-1 protein, His??
理论分子量17.57kDa
检测分子量17 kDa
性????状Lyophilized or Liquid
浓????度>0.5 mg/ml
物????种Human
序????列21-170/288
纯????度>95% as determined by SDS-PAGE
纯化方法AC
内毒素Not analyzed
表达系统E.coli
活性Not tested
标签His
缓?冲?液20 mM Tris-HCl (pH=9.0) with 8 M Urea
保存条件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases.
CD279 is an immunoglobulin superfamily member, also known as Programmed Cell Death 1. Programmed Cell Death 1 is expressed on a subset of CD4-CD8 thymocytes, and on activated T and B cells. Programmed Cell Death 1 is thought to be involved in lymphocyte clonal selection and peripheral tolerance. The Programmed Cell Death 1 ligands, PDL1 (also known as B7H1) and PDL2 (B7DC), are members of the B7 immunoglobulin superfamily.

SWISS:
Q15116

Gene ID:
5133

产品图片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.

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