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重组人白介素-1受体拮抗剂蛋白
产品名称:
重组人白介素-1受体拮抗剂蛋白
英文名称:
Recombinant human IL-1Ra protein, His
产品类别:
蛋白多肽
产品编号:
bs-0884P
保存条件:
Stored at -70℃ or -20℃. Avoid repeated freeze/thaw
[价格]
规格 价格 库存
100ug ¥ 2980.00 10

产品详情

产品编号bs-0884P
英文名称Recombinant human IL-1Ra protein, His
中文名称重组人白介素-1受体拮抗剂蛋白
别????名Recombinant Human Interleukin-1 receptor antagonist His Tag; Recombinant human IL-1Ra protein, His??
理论分子量17kDa
检测分子量20 kDa
性????状Lyophilized or Liquid
浓????度>0.5 mg/ml
物????种Human
序????列26-177/177
纯????度>95% as determined by SDS-PAGE
纯化方法AC
内毒素Not analyzed
表达系统E.coli
活性Not tested
标签His
缓?冲?液PBS (pH=7.4)
保存条件Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles.
注意事项This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
产品介绍IL-1RA is a member of the interleukin 1 cytokine family. IL1Ra is secreted by various types of cells including immune cells, epithelial cells, and adipocytes, and is a natural inhibitor of the pro-inflammatory effect of IL1β. This protein inhibits the activities of interleukin 1, alpha (IL1A) and interleukin 1, beta (IL1B), and modulates a variety of interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.

SWISS:
P18510

Gene ID:
3557


????L-lra-重组人白介素-1受体拮抗剂,通过与白细胞介素-1的Ⅰ型和Ⅱ型受体结合,特异性地阻断白细胞介素-1的生物学作用。白介素1受体拮抗剂(IL-1Ra)是体内天然的一种对IL-1有拮抗作用的细胞因子。国际上对其的研究愈来愈受到重视。 重组人白介素1受体拮抗剂(rhIL-1Ra)作为一种生物制剂已经FDA批准应用于临床治疗细胞因子。
????重组白介素1受体拮抗剂,分子量约17kD,纯度大于98%。
产品图片
The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.

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