产品分类/PRODUCT CLASSIFICATION
| 产品编号 | bs-43157P |
| 英文名称 | Recombinant SARS-Cov-2 Spike RBD protein (BQ.1.1/Omicron), His (HEK293) |
| 中文名称 | 重组SARS冠状病毒2 Spike突变蛋白RBD(BQ.1.1/Omicron) |
| 别????名 | SARS-CoV-2 spike protein; 2019-nCOV Spike protein; Spike glycoprotein; Spike protein S1; Surface glycoprotein; Spike protein RBD; SPIKE_SARS2?? |
| 理论分子量 | 26.7kDa |
| 性????状 | Lyophilized or Liquid |
| 物????种 | SARS-Cov-2 |
| 纯????度 | >90% as determined by SDS-PAGE |
| 内毒素 | Not analyzed |
| 表达系统 | HEK293 cell |
| 标签 | C-His |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 | The ongoing coronavirus disease 2019 (COVID-19) pandemic has prioritized the development of small-animal models for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The resulting mouse-adapted strain at passage 6 (called MASCp6) showed increased infectivity in mouse lung and led to interstitial pneumonia and inflammatory responses in both young and aged mice after intranasal inoculation. Deep sequencing revealed a panel of adaptive mutations potentially associated with the increased virulence. In particular, the N501Y mutation is located at the receptor binding domain (RBD) of the spike protein. SWISS: P0DTC2 Gene ID: 43740568 |
| 产品图片 |  Measured by its binding ability in a functional ELISA. Immobilized human ACE2, His-Avi Tag (Cat: bs-46001P) at 2μg/mL (100 μL/Well) can bind SARS-CoV-2 Spike RBD (BQ.1.1/Omicron), His Tag (Cat: bs-43157P), the EC50 is 34ng/mL.  The purity of the protein is greater than 90% as determined by reducing SDS-PAGE. |
