产品分类/PRODUCT CLASSIFICATION
| 产品编号 | bs-41408P |
| 英文名称 | Recombinant SARS-Cov-2 N protein, N-His |
| 中文名称 | 重组SARS冠状病毒2核衣壳蛋白 |
| 别????名 | SARS-CoV-2 Nucleocapsid Protein; SARS-CoV-2 NP; nucleocapsid protein [Severe acute respiratory syndrome coronavirus 2]; novel coronavirus N Protein; novel coronavirus Nucleocapsid Protein; 2019-nCoV Nucleoprotein; 2019-nCoV N; 2019nCoV N; 2019-nCoV N Protein; 2019 ncov N Protein; 2019-nCoV nucleocapsid protein; Recombinant SARS-Cov-2 N protein, His??新冠病毒N蛋白; 新冠N蛋白; SARS-CoV-2 N蛋白; |
 | Specific References??(6)?????|?????bs-41408P has been referenced in 6 publications. [IF=9.274]?Purva Sharma. et al. COVID-19–Associated Kidney Injury: A Case Series of Kidney Biopsy Findings. J Am Soc Nephrol. 2020 Sep;31(9):1948-1958??IHC?;??Human.?? [IF=8.109]?Romain Gasser. et al. Major role of IgM in the neutralizing activity of convalescent plasma against SARS-CoV-2. Cell Rep. 2021 Mar;34:108790??other?;?? [IF=8.008]?Juanzu Liu. et al. Immunoprofiling of Severity and Stage of Bacterial Infectious Diseases by Ultrabright Fluorescent Nanosphere-Based Dyad Test Strips. ANAL CHEM. 2022;94(24):8818–8826??IA?;??Human.?? [IF=6.232]?Shimaa Eissa. et al. Voltammetric-based immunosensor for the detection of SARS-CoV-2 nucleocapsid antigen. Microchim Acta. 2021 Jun;188(6):1-10??Other?;?? [IF=3.306]?Jia H. Ng. et al. Pathophysiology and Pathology of Acute Kidney Injury in Patients With COVID-19. Adv Chronic Kidney D. 2020 Sep;27:365??IHC?;??Human.?? [IF=2.089]?Wei Ling Lau. et al. The COVID-Kidney Controversy: Can SARS-CoV-2 Cause Direct Renal Infection?. Nephron. ;:1-5??IHC?;?? |
| 理论分子量 | 46kDa |
| 检测分子量 | 50 kDa |
| 性????状 | Lyophilized or Liquid |
| 浓????度 | ＞0.5 mg/ml |
| 物????种 | SARS-Cov-2 |
| 序????列 | 1-419/419 |
| 纯????度 | >95% as determined by SDS-PAGE |
| 纯化方法 | AC |
| 内毒素 | Not analyzed |
| 表达系统 | E.coli |
| 活性 | Not tested |
| 标签 | N-His |
| 缓?冲?液 | PBS (pH=7.4) |
| 保存条件 | Stored at -70℃ or -20℃. Avoid repeated freeze/thaw cycles. |
| 注意事项 | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
| 产品介绍 | Coronaviruses are enveloped viruses with a positive-sense RNA genome and with a nucleocapsid of helical symmetry. Coronavirus nucleoproteins localize to the cytoplasm and the nucleolus, a subnuclear structure, in both virus-infected primary cells and in cells transfected with plasmids that express N protein. Coronavirus N protein is required for coronavirus RNA synthesis, and has RNA chaperone activity that may be involved in template switch. Nucleocapsid protein is a most abundant protein of coronavirus. During virion assembly, N protein binds to viral RNA and leads to formation of the helical nucleocapsid. Nucleocapsid protein is a highly immunogenic phosphoprotein also implicated in viral genome replication and in modulating cell signaling pathways. Because of the conservation of N protein sequence and its strong immunogenicity, the N protein of coronavirus is chosen as a diagnostic tool. SWISS: P0DTC9 Gene ID: 43740575 |
| 产品图片 |  The purity of the protein is greater than 90% as determined by reducing SDS-PAGE.  The purity of the protein is greater than 90% as determined by reducing SDS-PAGE. |
