英文别名
A85B_MYCTU; Diacylglycerol acyltransferase/mycolyltransferase Ag85B; Mycobacterium tuberculosis Ag85B; M.tuberculosis Ag85b; EC:2.3.1.122; EC:2.3.1.20; DGAT; 30 kDa extracellular protein; Acyl-CoA:diacylglycerol acyltransferase; Antigen 85 complex B(85B; Ag85B); Extracellular alpha-antigen; Fibronectin-binding protein B(Fbps B); MTCY180.32; Rv1886c;
产品应用
WB=1:500-2000, ELISA=1:5000-10000
Not yet tested in other applications.
Optimal working dilutions must be determined by the end user.
交叉反应
Mycobacterium tuberculosis
免疫原
KLH conjugated synthetic peptide derived from Mycobacterium tuberculosis Ag85B : 231-325/325
纯化方法
affinity purified by Protein A
储存液
0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
相似性
Belongs to the mycobacterial A85 antigen family.
功能
Proteins of the antigen 85 complex are responsible for the high affinity of mycobacteria to fibronectin. Possesses a mycolyltransferase activity required for the biogenesis of trehalose dimycolate (cord factor), a dominant structure necessary for maintaining cell wall integrity.
保存条件
Shipped at 4℃. Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
注意事项
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
背景资料
Antigen 85B is the most abundant protein expressed by Mycobacterium tuberculosis (about one quarter). It is a myocolyc transferase in the myc pathway and catalyses - like Ag85A and Ag85C - the transfer of the fatty acid mycolate from one trehalose monomycolate to another, resulting in trehalose dimycolate and free trehalose and helping build the cell wall.
