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Purified anti-human IGFALS Antibody
产品名称:
Purified anti-human IGFALS Antibody
产品类别:
抗体
产品编号:
537302
产品应用:
537302
[价格]
规格 价格 库存
500µg ¥ 581 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Recombinant protein
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

ELISA Capture - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by ELISA assay. For ELISA Capture applications, a concentration range of 1.0 - 8.0 ?g/mL is recommended. To obtain a linear standard curve, serial dilutions of IGFALS recombinant protein ranging from 3.125 to 100 ng/mL is recommended for each ELISA plate. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

The pure M6005C04 antibody is useful as the capture antibody in a sandwich ELISA assay, when used in conjunction with the biotinylated M6001E07 antibody (Cat. No. 537404) as the detection antibody and Recombinant Human IGFALS (ELISA Std.) (Cat. No. 758809).

Product Citations
  1. Kimura Y, et al. 2021. Sci Rep. 11:20638. PubMed
RRID
AB_2783348 (BioLegend Cat. No. 537302)

Antigen Details

Distribution

Produced by the liver and is mainly found in the postnatal serum.

Function
IGFALS production is stimulated by growth hormone and is important for extending the serum half life of IGF.
Interaction
IGF-1/IGF-2 and IGFBP-3/IGFBP-5 binary complexes
Biology Area
Angiogenesis, Cancer Biomarkers, Cell Biology, Cell Cycle/DNA Replication, Cell Proliferation and Viability, Signal Transduction
Molecular Family
Carrier Proteins
Antigen References
  1. Baxter RC, Dai J. 1994. Endocrinology. 134:848-852.
  2. Twigg SM, Baxter RC. 1998. J Biol Chem. 273(11):6074-9.
  3. Khosravi MJ, et al. 1997. J Clin Endocrinol Metab. 82:3944-3951.
  4. Domene HM, et al. 2004. New Eng J Med. 350:570-577.
  5. Domene HM, et al. 2005. J Endocrinol Invest. 28(5):43-6.
Gene ID
3483 View all products for this Gene ID
UniProt
View information about IGFALS on UniProt.org

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