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Purified anti-Aggrecan Antibody
产品名称:
Purified anti-Aggrecan Antibody
产品类别:
抗体
产品编号:
674902
产品应用:
674902
[价格]
规格 价格 库存
100µg ¥ 265 1

产品详情

Product Details

Verified Reactivity
Human
Antibody Type
Monoclonal
Host Species
Mouse
Immunogen
Recombinant human Aggrecan produced in 293E cells.
Formulation
Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation
The antibody was purified by affinity chromatography.
Concentration
0.5 mg/ml
Storage & Handling
The antibody solution should be stored undiluted between 2°C and 8°C.
Application

WB - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.25 - 2.0 ?g per ml. It is recommended that the reagent be titrated for optimal performance for each application.

Application Notes

This antibody works for Western blotting under non-reducing conditions.

RRID
AB_2565486 (BioLegend Cat. No. 674902)

Antigen Details

Structure
2415 amino acids with a predicted molecular weight of approximately 250 kD.
Distribution

Chondrocytes and embryonic brain glia.

Function
Plays a key role in neural development, glial scar formation, cell adhesion, cell growth, receptor binding, cell migration, and interaction with other extracellular matrix constituents.
Ligand/Receptor
Aggrecan is an enzymatic substrate of MMPs and ADAMT11. It interacts with versican, which is a large ECM proteoglycan.
Biology Area
Cell Biology, Signal Transduction
Antigen References

1. Doege KJ, et al. 1991. J. Biol. Chem. 266:894.
2. Nap RJ and Szleifer I. 2008. Biophys. J. 95:4570.
3. Roughley P, et al. 2006. Eur. Cell Mater. 11:1.
4. Kiani C, et al. 2002. Cell Res. 12:19-32.
5. Melin Fürst C, et al. 2013. PLoS One 8:e61407.

Gene ID
176 View all products for this Gene ID
UniProt
View information about Aggrecan on UniProt.org

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