Biotin anti-human MMP-9 Antibody
- 产品名称:
- Biotin anti-human MMP-9 Antibody
- 产品类别:
- 抗体
- 产品编号:
- 532101
- 产品应用:
- 532101
- Verified Reactivity
- Human
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant Human MMP-9
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
- Preparation
- The antibody was purified by affinity chromatography, and conjugated with biotin under optimal conditions.
- Concentration
- 0.5 mg/ml
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C. Do not freeze.
- Application
-
ELISA Detection - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by ELISA assay. For use as an ELISA detection antibody, a concentration of 0.25?g/ml is recommended. To obtain a linear standard curve, serial dilutions of human MMP-9 protein ranging from 5 to 0.078 ng/ml are recommended for each ELISA plate when paired with M2101G05 (Cat. No. 681802). It is recommended that the reagent be titrated for optimal performance for each application.
- Application Notes
ELISA Detection: The biotinylated M2108F07 antibody is useful as a detection antibody for a sandwich ELISA assay, when used in conjunction with purified M2101G05 (Cat. No. 681802) antibody as the capture antibody.
Note:?For testing human MMP-9 in serum or plasma, BioLegend's LEGEND MAX? Kit (Cat. No. 444907) is specially developed and recommended.
- RRID
- AB_2734495 (BioLegend Cat. No. 532101)
- Distribution
-
MMP-9 is expressed by alveolar macrophages, granulocytes, fibroblasts, and fibrosarcoma cells.
- Function
- Degradation of extracellular matrix (ECM) and connective tissue proteins, angiogenesis, tissue remodeling, and cancer metastasis. Regulates chemokine activity. Inhibited by TIMPs and α2-macroglobulin (inhibitor of MMPs in bodily fluids).
- Interaction
- ECM proteins
- Ligand/Receptor
- TIMPs
- Cell Type
- Macrophages, Granulocytes, Fibroblasts
- Biology Area
- Angiogenesis, Cell Adhesion, Cell Biology, Neuroinflammation, Neuroscience
- Molecular Family
- Enzymes and Regulators
- Antigen References
-
- Chakrabarti S, Patel KD. 2005.?Exp. Lung Res.?31:599.
- Klein T, Bischoff R. 2011.?Amino Acids.?41:271.
- Raffetto JD, Khalil RA. 2008.?Biochem. Pharmacol.?75:346.
- Bourboulia D, Stetler-Stevenson WG. 2010.?Semin. Cancer Biol.?20:161.
- Vilen ST,?et al.?2013.?Scientific World Journal.?920595.
- Gene ID
- 4318 View all products for this Gene ID
- UniProt
- View information about MMP-9 on UniProt.org