PE anti-human CD301 (CLEC10A) Antibody
- 产品名称：
- PE anti-human CD301 (CLEC10A) Antibody
- 产品类别：
- 抗体
- 产品编号：
- 354703
- 产品应用：
- 354703
- Verified Reactivity
- Human
- Reported Reactivity
- African Green, Baboon, Cynomolgus
- Antibody Type
- Monoclonal
- Host Species
- Mouse
- Immunogen
- Recombinant CD301 (extracellular domain)
- Formulation
- Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and BSA (origin USA)
- Preparation
- The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions.
- Concentration
- Lot-specific (to obtain lot-specific concentration, please enter the lot number in our Concentration and Expiration Lookup or Certificate of Analysis online tools.)
- Storage & Handling
- The antibody solution should be stored undiluted between 2°C and 8°C, and protected from prolonged exposure to light. Do not freeze.
- Application
-
FC - Quality tested
- Recommended Usage
Each lot of this antibody is quality control tested by immunofluorescent staining with flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is 5 ?l per million cells in 100 ?l staining volume or 5 ?l per 100 ?l of whole blood.
- Excitation Laser
- Blue Laser (488 nm)
Green Laser (532 nm)/Yellow-Green Laser (561 nm)
- Application Notes
H037G3 antibody binding is divalent cation dependent.
- Product Citations
-
- Iwabuchi R, et al. 2021. Frontiers in Immunology. 12:643040. PubMed
- Heger L, et al. 2018. Front Immunol. 9:744. PubMed
- Mulder K, et al. 2021. Immunity. 54(8):1883-1900.e5. PubMed
- Brulefert A, et al. 2021. Allergy. 76:2044. PubMed
- Dutertre CA, et al. 2020. Immunity. 51(3):573-589.e8.. PubMed
- RRID
- AB_11219202 (BioLegend Cat. No. 354703) AB_11219002 (BioLegend Cat. No. 354704)
- Structure
- 40 kD type II transmembrane glycoprotein, consists of a 39 amino acid (aa) cytoplasmic region, a 21 aa transmembrane segment and a 256 aa extracellular domain (ECD) with one carbohydrate recognition domain (CRD) and a neck region
- Distribution
-
Immature myeloid dendritic cells, activated macrophages
- Function
- Cell adhesion, cell-cell signaling, glycoprotein turnover, inflammation, immune response
- Interaction
- Carbohydrate determinants, GP envelope glycoprotein on Marburg and Ebola viruses
- Ligand/Receptor
- Glycans containing terminal GalNAc moieties
- Cell Type
- Dendritic cells, Macrophages
- Biology Area
- Cell Adhesion, Cell Biology, Immunology, Innate Immunity, Signal Transduction
- Molecular Family
- Adhesion Molecules, CD Molecules
- Antigen References
-
1. Van Vliet SJ, et al. 2006. Nat. Immunol. 7:1200.
2. Higashi N, et al. 2002. J. Biol. Chem. 277:20686.
3. Tsuiji M, et al. 2002. J. Biol. Chem. 277:28892.
4. Valladeau J, et al. 2001. J. Immunol. 167:5767.
5. Suzuki N, et al. 1996. J. Immunol. 156:128.
- Gene ID
- 10462 View all products for this Gene ID
- UniProt
- View information about CD301 on UniProt.org
