Purified anti-LIF Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 229	1

规格

价格

库存

100µg

￥ 229

Product Details

Verified Reactivity: Mouse, Human
Antibody Type: Monoclonal
Host Species: Rat
Immunogen: Recombinant mouse LIF produced in E. coli.
Formulation: Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Preparation: The antibody was purified by affinity chromatography.
Concentration: 0.5 mg/ml
Storage & Handling: The antibody solution should be stored undiluted between 2°C and 8°C.
Application: WB - Quality tested
ICC - Verified
Recommended Usage: Each lot of this antibody is quality control tested by Western blotting. For Western blotting, the suggested use of this reagent is 0.25 - 2.0 ?g per mL. For immunocytochemistry, a concentration range of 2.0 - 10 μg/ml is recommended. It is recommended that the reagent be titrated for optimal performance for each application.
RRID: AB_2565278 (BioLegend Cat. No. 674702)

Structure: 202 amino acids with a predicted molecular weight of approximately 22 kD.
Distribution: Expressed in the trophectoderm of the developing embryo, activated CD4⁺ T cells.
Function: Inhibits embryonic stem cell differentation and induces the terminal differentiation of myeloid leukemia cells. LIF is upregulated by TNF-α and IL-17. LIF is downregulated by IL-4 and IL-13 in fibroblasts.
Interaction: Embryonic stem cells.
Ligand/Receptor: LIF receptor complex (gp190 and gp130).
Cell Type: T cells, Tregs
Biology Area: Cell Biology, Immunology
Molecular Family: Cytokines/Chemokines, Growth Factors
Antigen References: 1. Moreau JF, et al. 1988. Nature 336:690.
2. Tomida M, et al. FEBS Lett. 334:193.
3. Metcalfe SM. 2011. Genes Immun. 12:157.
4. Voyle RB, et al. 1999. Exp. Cell Res. 249:199.
5. Slaets H, et al. 2010. Trends Mol. Med. 16:493.
6. Souza PP, et al. 2012. Mol. Immunol. 49:601
Gene ID: 3976 View all products for this Gene ID
UniProt: View information about LIF on UniProt.org