Purified anti-VEGF-165 Antibody -上海雅吉生物科技有限公司

规格	价格	库存
100µg	￥ 124	1

规格

价格

库存

100µg

￥ 124

Product Details

Verified Reactivity

Human

Antibody Type

Monoclonal

Host Species

Mouse

Immunogen

Human VEGF-165

Formulation

Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.

Preparation

The antibody was purified by affinity chromatography.

Concentration

0.5 mg/ml

Storage & Handling

The antibody solution should be stored undiluted between 2°C and 8°C.

Application

IP - Quality tested

Recommended Usage

Each lot of this antibody is quality control tested by?immunoprecipitation. This antibody can be used at 2 - 10 ?g/mL?for immunoprecipitation. It is recommended that the reagent be titrated for optimal performance for each application.

Product Citations

Kumanishi S, et al. 2019. Int J Oncol. 55:167. PubMed

RRID

AB_2564372 (BioLegend Cat. No. 662702)

Antigen Details

Structure: 232 amino acids with predicted molecular weight of approximately 27 kD.
Distribution: Widely expressed.
Function: Endothelial cell proliferation, angiogenesis, and vasculogenesis.
Interaction: Binds to heparin sulfate, heparin, and neuropilin-1. Interacts with vascular endothelial cells, monocytes, and macrophages, which express VEGFR1; this induces proliferation of endothelial cells and stimulates the migration of monocytes and macrophages.
Ligand/Receptor: FLT1/VEGFR1 and KDR/VEGFR2.
Biology Area: Angiogenesis, Apoptosis/Tumor Suppressors/Cell Death, Cell Biology, Cell Cycle/DNA Replication, Cell Motility/Cytoskeleton/Structure, Immunology, Signal Transduction
Molecular Family: CD Molecules, Cytokine/Chemokine Receptors
Antigen References: 1. Conn G, et al. 1990. Proc. Natl. Acad. Sci. USA 87:1323.
2. Gerber H, et al. 2002. Nature 417:954.
3. Shibuya M, et al. 2006. J. Biochem. Mol. Biol. 39:469.
4. Reddy K, et al. 2008. Angiogenesis 11:257.
5. Monaghan-Benson E, et al. 2010. Am. J. Pathol. 177:2091.
6. Koch S and Claesson-Welsh L. 2012. Cold Spring Harb. Perspect. Med. 2:a006502.
7. Cao Y. 2014. Nat. Rev. Endocrinol. 10:530.
8. Lui KO. 2014. Curr. Stem Cell Res. Ther. 9:396.
Gene ID: 7422 View all products for this Gene ID
UniProt: View information about VEGF-A on UniProt.org

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